Results 41 to 50 of about 113,957,618 (180)

Characterization and Evolutionary Analysis of a Novel H3N2 Influenza A Virus Glycosylation Motif in Southern China

Frontiers in Microbiology, 2020
An influenza A (H3N2) virus epidemic occurred in China in 2017 and the causative strain failed to bind red blood cells (RBCs), which may affect receptor binding and antibody recognition.
Zhiqi Zeng, Lee-Fong Yau, Zengxian Lin, Xuanzi Xia, Zifeng Yang, Zifeng Yang, Jing-Rong Wang, Wenjun Song, Wenjun Song, Xinhua Wang, Xinhua Wang   +10 more
doaj   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Estimating the impact of influenza vaccination and antigenic drift on influenza-related morbidity and mortality in England & Wales using hidden Markov models [PDF]

Influenza causes substantial morbidity and mortality in some influenza sea- sons, especially among the elderly. Influenza seasons dominated by circula- tion of influenza A/H3N2 virus tend to result in more morbidity and mor- tality than seasons ...
Mann, Andrea Gail
core   +1 more source

End of season 2022/2023 quadrivalent influenza vaccine effectiveness in preventing influenza in primary care in Portugal

Human Vaccines & Immunotherapeutics, 2023
Using a test-negative case–control design, we aim to estimate influenza vaccine effectiveness (VE) against medically attended laboratory-confirmed influenza in Portugal in 2022/2023 season. Between week 41/2022 and week 14/2023, data on 592 patients with
Irina Kislaya, Ana Rita Torres, Licínia Gomes, Aryse Melo, Ausenda Machado, Camila Henriques, Nuno Verdasca, Raquel Guiomar, Ana Paula Rodrigues, National Influenza Surveillance Network   +9 more
doaj   +1 more source

Competitive SELEX Strategy for High‐Affinity Aptamer Isolation and Enhanced Biosensing

Small, EarlyView.
A novel competitive SELEX strategy was developed to isolate high‐affinity aptamers by using a lower‐affinity competitor during the selection process. This approach enabled the identification of an aptamer with exceptional binding affinity, significantly improving target detection sensitivity.
Jiuxing Li, Jiaxuan Xiao, Jimmy Gu, Zhen Zhang, Yingfu Li   +4 more
wiley   +1 more source

Phosphoproteomics to Characterize Host Response During H3N2 Canine Influenza Virus Infection of Dog Lung

Frontiers in Veterinary Science, 2020
Avian-origin H3N2 canine influenza viruses (CIVs) cause severe contagious respiratory disease in dogs, and quickly adapt to new environments. To further understand the mechanism of virus infection and host-virus interactions, we characterized the ...
Yongbo Liu, Yongbo Liu, Yongbo Liu, Cheng Fu, Shaotang Ye, Shaotang Ye, Shaotang Ye, Yingxin Liang, Yingxin Liang, Yingxin Liang, Zhonghe Qi, Zhonghe Qi, Zhonghe Qi, Congwen Yao, Congwen Yao, Congwen Yao, Zhen Wang, Zhen Wang, Zhen Wang, Ji Wang, Ji Wang, Ji Wang, Siqi Cai, Siqi Cai, Siqi Cai, Shiyu Tang, Shiyu Tang, Shiyu Tang, Ying Chen, Ying Chen, Ying Chen, Shoujun Li, Shoujun Li, Shoujun Li   +33 more
doaj   +1 more source

Hj‐aggregates of quinoline‐fused boron‐dipyrromethene nanoparticles for near‐infrared dualmodal photodynamic and photothermal therapy

Smart Molecules, EarlyView.
A novel quinoline‐fused cyclic pyrrole is synthesized via lithium diisopropylamide‐catalyzed [3 + 2] cyclization, enabling the construction of a symmetrical boron‐dipyrromethene photosensitizer that forms Hj‐aggregates upon nanoparticle encapsulation.
Bo Zhang, Chuang Du, Yuewen Yang, Dongping Xu, Xin‐Dong Jiang, Hui‐Xin Liu, Gaowu Qin   +6 more
wiley   +1 more source

The order of infection shapes disease outcomes in influenza and herpes simplex virus coinfection by modulating immune responses

Virology Journal
Background Coinfections of influenza A virus (IAV) and herpes simplex virus type 1 (HSV-1) have been increasingly reported in patients with severe pneumonia, yet their pathogenesis remains poorly understood.
Yuanjun Lyu, Kailin Mai, Hongxuan Zhou, Chunguang Yang, Yunceng Weng, Zhenhui Zhang, Yang Wang, Zifeng Yang   +7 more
doaj   +1 more source

The V223I substitution in hemagglutinin reduces the binding affinity to human-type receptors while enhancing the thermal stability of the H3N2 canine influenza virus

Frontiers in Microbiology
Given the intimate relationship between humans and dogs, the H3N2 canine influenza viruses (CIVs) pose a threat to public health. In our study, we isolated four H3N2 CIVs from 3,758 dog nasal swabs in China between 2018 and 2020, followed by genetic and ...
Liling Liu, Fujun Wang, Fujun Wang, Ying Wu, Weiyong Mi, Yaping Zhang, Lei Chen, Dongxue Wang, Guohua Deng, Jianzhong Shi, Hualan Chen, Huihui Kong   +11 more
doaj   +1 more source

Synergistic Effect of Ambient Ozone, Relative Humidity, and Temperature on Epidemic Patterns of Influenza: A Hypothesis and Its Verification

Microbiology and Immunology, EarlyView.
ABSTRACT The mechanisms underlying seasonal patterns in influenza epidemics have long been an enigma. Our laboratory study revealed that ambient ozone significantly inactivates airborne influenza viruses synergistically with higher relative humidity and temperature.
Hidekazu Nishimura, Soichiro Sakata, Julian W. Tang, Suguru Ohmiya, Masanori Katsumi, Takahiro Yokoyama   +5 more
wiley   +1 more source