Results 21 to 30 of about 28,370 (183)

An Outbreak of Influenza A (H3N2) in a Nursing Home

Journal of the Japanese Association for Infectious Diseases, 1996
In the nursing home belonging to our hospital, an outbreak of influenza A (H3N2) occurred in January 1995, and we studied 23 elderly residents with influenza A infection. Twenty three residents with influenza A (8 males and 15 females) ranged in age from 67 to 95 years (average 83.1 years), 91.3% of them were bedridden.
YAMAKOSHI, Masahiro, SUZUKI, Kanzou, YAMAMOTO, Toshinobu, YAMAMOTO, Toshiyuki, GOTO, Noriko, NAKAKITA, Takashi, YAMANAKA, Katsumi   +6 more
openaire   +3 more sources

Early Prediction of Antigenic Transitions for Influenza A H3N2

PLOS Computational Biology, 2019
Abstract Influenza A/H3N2 is a rapidly evolving virus which experiences major antigenic transitions every two to eight years. Anticipating the timing and outcome of transitions is critical to developing effective seasonal influenza vaccines.
Lauren A. Castro, Trevor Bedford, Lauren Ancel Meyers   +2 more
openaire   +4 more sources

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

npj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard, Jennifer DeBeauchamp, Matthew J. Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J. Webby, Eric A. Weaver   +6 more
doaj   +1 more source

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

Microbiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie   +10 more
doaj   +1 more source

Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses

npj Vaccines, 2022
History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied.
Nina Urke Ertesvåg, Rebecca Jane Cox, Sarah Larteley Lartey, Kristin G-I Mohn, Karl Albert Brokstad, Mai-Chi Trieu   +5 more
doaj   +1 more source

A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019–2020

Viruses, 2022
Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously damaged human life and health. To assess the
Tengfei Liu, Yuhao Huang, Shumin Xie, Lingyu Xu, Junhong Chen, Wenbao Qi, Ming Liao, Weixin Jia   +7 more
doaj   +1 more source

H3N2 Canine Influenza Virus Infection in a Dog [PDF]

Veterinary Pathology, 2016
In 2015, H3N2 canine influenza emerged in dogs in the greater Chicago area. During this time, a 10-year-old German Shepherd dog presented to the referring veterinarian with lethargy and coughing that quickly progressed to death. This report describes the macroscopic and microscopic lesions and the molecular testing performed to identify the novel North
C E, Watson, C, Bell, K, Toohey-Kurth
openaire   +2 more sources

Novel reassortant swine H3N2 influenza A viruses in Germany [PDF]

Scientific Reports, 2020
AbstractAnalysis of 228 H3N2 swine influenza A virus isolates collected between 2003 and 2015 in Germany revealed important changes in molecular epidemiology. The data indicate that a novel reassortant, Rietberg/2014-like swine H3N2, emerged in February 2014 in Northern Germany.
Zell, Roland, Groth, Marco, Krumbholz, Andi, Jeannette, Lange, Philipps, Anja, Dürrwald, Ralf   +5 more
openaire   +4 more sources

Molecular Epidemiology of Influenza A(H3N2) Virus Reinfections [PDF]

The Journal of Infectious Diseases, 2002
Between 1979 and 1989, families enrolled in the Houston Family Study were prospectively monitored for influenza virus infections. Reinfection with the H3N2 subtype occurred in a number of family members, and 6 pairs of isolates (interval between collection of first and second isolate, 2-5 years) were available for molecular analysis.
Catherine B, Smith, Nancy J, Cox, Kanta, Subbarao, Larry H, Taber, W Paul, Glezen   +4 more
openaire   +2 more sources

Molecular identification of neuraminidase gene mutations in influenza A/H1N1 and A/H3N2 isolates of Mazandaran province, north of Iran

Journal of Global Antimicrobial Resistance
Objectives: The neuraminidase (NA) mutations causing resistance to NA inhibitors (NAIs) mostly compromise the fitness of influenza viruses. Considering the importance of these mutations, constant monitoring of the effectiveness of available drugs is ...
Mehdi Rabie-Rudsari, Emad Behboudi, Ategheh Ranjkesh, Kimia Kaveh, Hadi Razavi-Nikoo, Mohammad Reza Haghshenas, Abdolvahab Moradi   +6 more
doaj   +1 more source