Results 31 to 40 of about 28,370 (183)

H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs

Microbiology Spectrum
In 2016, a distinct branch of H3N2 canine influenza virus (CIV) emerged, which has mutations related to mammalian adaptation and has replaced previously prevalent strains. This branch poses a risk of zoonotic infection.
Fei-fei Ge, Li-pin Shen, De-quan Yang, Xian-cao Yang, Xin Li, Hai-xiao Shen, Jian Wang, Shixin Huang   +7 more
doaj   +1 more source

Transmission of Avian Influenza Virus (H3N2) to Dogs

Emerging Infectious Diseases, 2008
In South Korea, where avian influenza virus subtypes H3N2, H5N1, H6N1, and H9N2 circulate or have been detected, 3 genetically similar canine influenza virus (H3N2) strains of avian origin (A/canine/Korea/01/2007, A/canine/Korea/02/2007, and A/canine/Korea/03/2007) were isolated from dogs exhibiting severe respiratory disease.
Daesub Song, Bokyu Kang, Chulseung Lee, Linda J. Saif, Gunwoo Ha, Dongseok Kang, Seongjun Park, Bongkyun Park, Jinsik Oh   +8 more
openaire   +3 more sources

H3N2 Virus Outbreak: A latest global threat

Journal of Zoonotic Diseases, 2023
The current H3N2 virus outbreak has sent shockwaves worldwide, with health officials rushing to stop its spread. This form of influenza has been wreaking havoc around the globe, culminating in an alarming number of hospitalizations and fatalities.
Manisha Vohra , Mohammad Amir , Amit Sharma , Ian Osoro   +3 more
doaj   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Evolution-informed forecasting of seasonal influenza A (H3N2) [PDF]

Science Translational Medicine, 2017
ABSTRACT Inter-pandemic or seasonal influenza exacts an enormous annual burden both in terms of human health and economic impact. Incidence prediction ahead of season remains a challenge largely because of the virus’ antigenic evolution.
Du, Xiangjun, King, Aaron A., Woods, Robert J., Pascual, Mercedes   +3 more
openaire   +2 more sources

Amantadine-resistant influenza A (H3N2) viruses in Iran

Acta Virologica, 2009
Adamantanes have been used for the prophylaxis and treatment of Influenza A virus (IAV) infections worldwide. However, they have limited use because of increasing number of resistant viruses during recent years. In investigating the frequency of amantadine-resistant IAVs (H3N2) circulating in Iran in 2005-2008, we found that M2 sequences of recently ...
Yavarian, J., Azad, T., Jandaghi, N., Nategh, R.   +3 more
openaire   +2 more sources

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Comparative Analysis of Whole-Transcriptome RNA Expression in MDCK Cells Infected With the H3N2 and H5N1 Canine Influenza Viruses

Frontiers in Cellular and Infection Microbiology, 2019
This study aimed to detect changes in the complete transcriptome of MDCK cells after infection with the H5N1 and H3N2 canine influenza viruses using high-throughput sequencing, search for differentially expressed RNAs in the transcriptome of MDCK cells ...
Pan Tao, Pan Tao, Pan Tao, Zhangyong Ning, Xiangqi Hao, Xiangqi Hao, Xiangqi Hao, Xi Lin, Xi Lin, Xi Lin, Qingxu Zheng, Qingxu Zheng, Qingxu Zheng, Shoujun Li, Shoujun Li, Shoujun Li   +15 more
doaj   +1 more source

Changes in the Nasal Microbiota of Pigs Following Single or Co-Infection with Porcine Reproductive and Respiratory Syndrome and Swine Influenza A Viruses

Pathogens, 2021
Host-microbiota interactions are important in shaping immune responses that have the potential to influence the outcome of pathogen infection. However, most studies have focused on the gut microbiota and its possible association with disease outcome ...
Tiphany Chrun, Joy Leng, Roberto M. La Ragione, Simon P. Graham, Elma Tchilian   +4 more
doaj   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source