Results 61 to 70 of about 113,957,618 (180)

Molecular analysis of influenza A(H3N2) in a remote tropical island during 2014-2019 to identify the frequency of introduction and local circulation

International Journal of Infectious Diseases
Background: The sources of new antigenic Influenza A(H3N2) variants and the role of tropical regions in the global A(H3N2) circulation remain unclear.
Sikandar Azam, Takeaki Imamura, Michiko Okamoto, Yusuke Sayama, Mayuko Saito, Mariko Saito-Obata, Clyde Dapat, Raita Tamaki, Christina Dahlia Joboco, Joanna Ina Manalo, Samantha Louise Bado, Joanne De Jesus Cornejo, Socorro Lupisan, Marianette Inobaya, Veronica Tallo, Beatriz P Quiambao, Hitoshi Oshitani   +16 more
doaj   +1 more source

Sequence Characterization of matrix protein (M1) in influenza A viruses (H1, H3 and H5)

Microbiology Research, 2011
This study brings the analysis of amino acid sequences of matrix protein (M1) from the influenza virus A (H1N1, H3N2 and H5N1) during 2007-2208. 741 sequences of M1 were compared, of them, H1N1 388; H3N2 251 and H5N1 102.
Jun Zhang, Xiao Ling Yu, Lei Xu, Fang Zhi Li, Yong Gang Li   +4 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Genetic drift influenza A(H3N2) virus hemagglutinin (HA) variants originated during the last pandemic turn out to be predominant in the 2011-2012 season in Northern Italy

, 2013
Influenza A(H3N2) virus is once again the predominant strain after the 2009 pandemic. Its molecular epidemiology and phylogeny were investigated during the 2011-2012 season in Northern Italy. The epidemiological and virological influenza surveillance was
E. Pariani, E. Ebranati, A. Amendola, A. Lai, G. Zehender, A.R. Zanetti, A. Ranghiero, G. Anselmi   +7 more
core   +1 more source

Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets [PDF]

, 2011
Recent isolation of a novel swine-origin influenza A H3N2 variant virus [A(H3N2)v] from humans in the United States has raised concern over the pandemic potential of these viruses.
Belser, Jessica A., Maines, Taronna R., Sun, Xiangjie, Jayaraman, Akila, Pappas, Claudia, Raman, Rahul, Pearce, Melissa B., Zeng, Hui, Katz, Jacqueline M., Cox, Nancy J., Sasisekharan, Ram, Gustin, Kortney M., Tumpey, Terrence M.   +12 more
core   +1 more source

LUNG DAMAGE IN CHILDREN WITH INFLUENZA

Детские инфекции (Москва), 2015
The article presents the results of clinical and laboratory studies of patients with influenza complicated by pneumonia. Peculiarities of clinical manifestations of pneumonia caused by influenza virus have been disclosed.
D. A. Vorobeva, L. N. Guseva, I. E. Koltunov, A. V. Bullih, S. B. Yatsyshina, G. A. Shipulin, E. L. Tumanova, N. A. Malyshev, V. F. Uchaykin   +8 more
doaj   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

A live-attenuated influenza vaccine for H3N2 canine influenza virus

, 2017
Canine influenza is a contagious respiratory disease in dogs caused by two subtypes (H3N2 and H3N8) of canine influenza virus (CIV). Currently, only inactivated influenza vaccines (IIVs) are available for the prevention of CIVs.
Parrish, Colin R., Nogales, Aitor, Martinez Sobrido, Luis, Pablo R. Murcia, Emma C. Reilly, David J. Topham, Aitor Nogales, Laura Rodriguez, Murcia, Pablo R., Colin R. Parrish, Reilly, Emma C., Luis Martinez Sobrido, Rodriguez, Laura, Topham, David J.   +13 more
core   +1 more source

Genetic Drift of Influenza A(H3N2) Viruses During Two Consecutive Seasons in 2011-2013 in Corsica, France

, 2013
The 2011-2012 and 2012-2013 post-pandemic influenza outbreaks were characterized by variability in the A(H3N2) influenza viruses, resulting in low to moderate vaccine effectiveness (VE).
de Lamballerie XN, Blanchon T, Falchi A., Arena C, Fantoni A, Salez N, CORRIAS, LAURA, Amoros JP, Varesi L   +8 more
core   +1 more source

Prior immunity to seasonal influenza A(H3N2) virus confers varying levels of cross-protection against challenge with clade 2.3.4.4b A(H5N1), A(H7N9), or A(H9N2) virus in a ferret model

Microbiology Spectrum
Evaluating how prior immunity to seasonal influenza viruses influences subsequent zoonotic influenza A virus (IAV) infection in animal models is critical for pandemic preparedness.
Xiangjie Sun, Jessica A. Belser, Zhu-Nan Li, Feng Liu, Nicole Brock, Joanna A. Pulit-Penaloza, Troy J. Kieran, Claudia Pappas, Hui Zeng, Jessie C. Chang, Paul J. Carney, Brandon L. Bradley-Ferrell, James Stevens, Min Z. Levine, Terrence M. Tumpey, Taronna R. Maines   +15 more
doaj   +1 more source