Results 11 to 20 of about 41,419 (260)

The GPI-Anchored GH76 Protein Dfg5 Affects Hyphal Morphology and Osmoregulation in the Mycoparasite Trichoderma atroviride and Is Interconnected With MAPK Signaling

Frontiers in Microbiology, 2021
The fungal cell wall is composed of a cross-linked matrix of chitin, glucans, mannans, galactomannans, and cell wall proteins with mannan chains. Cell wall mannans are directly attached to the cell wall core, while the majority of mannoproteins is ...
Lea Atanasova, Lea Atanasova, Dubraska Moreno-Ruiz, Clemens Grünwald-Gruber, Clemens Grünwald-Gruber, Viktoria Hell, Susanne Zeilinger   +6 more
doaj   +1 more source

Can Scoliotic Discs Be Controls for Molecular Studies in Intervertebral Disc Research? Insights From Proteomics

Global Spine Journal, 2022
Study Design: Proteomic analysis of human intervertebral discs. Objectives: To compare the characters of scoliotic discs and discs from magnetic resonance imaging (MRI)–normal voluntary organ donors controls used in disc research employing proteomics and
S. Rajasekaran MS, DNB, FRCS, MCh, PhD, Chitraa Tangavel MSc, MPhil, PhD, K. S. Sri Vijay Anand MS, FISS, Dilip Chand Raja Soundararajan MS, DNB, FNB, Sharon Miracle Nayagam MSc, R. Sunmathi MTech, M. Raveendran MSc, PhD, Ajoy Prasad Shetty MS, DNB, Rishi Mugesh Kanna MS, MRCS, FNB, B. T. Pushpa DNB, FRCR   +9 more
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Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction

Scientific Reports, 2022
Persulfidation contributes to a group of redox post-translational modifications (PTMs), which arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) action.
Hedvika Řimnáčová, Jiří Moravec, Miriama Štiavnická, Jiřina Havránková, Ladan Monsef, Petr Hošek, Šárka Prokešová, Tereza Žalmanová, Tereza Fenclová, Jaroslav Petr, Milena Králíčková, Jan Nevoral   +11 more
doaj   +1 more source

p27^Kip1, an Intrinsically Unstructured Protein with Scaffold Properties

Cells, 2021
The Cyclin-dependent kinase (CDK) regulator p27Kip1 is a gatekeeper of G1/S transition. It also regulates G2/M progression and cytokinesis completion, via CDK-dependent or -independent mechanisms.
Debora Bencivenga, Emanuela Stampone, Domenico Roberti, Fulvio Della Ragione, Adriana Borriello   +4 more
doaj   +1 more source

A-kinase anchoring proteins take shape [PDF]

Current Opinion in Cell Biology, 2007
A-kinase anchoring proteins (AKAPs) are signaling scaffolds that contribute to various aspects of cAMP signaling. They do this by tethering protein kinase-A to specific subcellular sites, thereby focusing its activity toward relevant substrates.
Darren L, Beene, John D, Scott
openaire   +2 more sources

Re-expression of AKAP12 inhibits progression and metastasis potential of colorectal carcinoma in vivo and in vitro. [PDF]

PLoS ONE, 2011
BACKGROUND: AKAP12/Gravin (A kinase anchor protein 12) is one of the A-kinase scaffold proteins and a potential tumor suppressor gene in human primary cancers.
Weiwei Liu, Ming Guan, Tingting Hu, Xiaoye Gu, Yuan Lu   +4 more
doaj   +1 more source

Anchoring proteins encounter mitotic kinases [PDF]

Cell Cycle, 2013
Defective progression of cells through mitosis permits an accumulation of genetic defects that lead to aneuploidy. Cells in a state of aneuploidy acquire mutations that eventually cause their transformation from normal cells into cancer.1 Recent evidence suggests that perturbing the spatial and temporal pattern of cell division can enhance such ...
Canton, David A., Scott, John D.
openaire   +2 more sources

Transmembrane Peptides as Inhibitors of Protein-Protein Interactions: An Efficient Strategy to Target Cancer Cells?

Frontiers in Oncology, 2020
Cellular functions are regulated by extracellular signals such as hormones, neurotransmitters, matrix ligands, and other chemical or physical stimuli.
Camille Albrecht, Camille Albrecht, Aline Appert-Collin, Aline Appert-Collin, Dominique Bagnard, Dominique Bagnard, Sébastien Blaise, Sébastien Blaise, Béatrice Romier-Crouzet, Béatrice Romier-Crouzet, Roman G. Efremov, Roman G. Efremov, Hervé Sartelet, Hervé Sartelet, Laurent Duca, Laurent Duca, Pascal Maurice, Pascal Maurice, Amar Bennasroune, Amar Bennasroune   +19 more
doaj   +1 more source

Cypher/ZASP Is a Novel A-kinase Anchoring Protein [PDF]

Journal of Biological Chemistry, 2013
PKA signaling is important for the post-translational modification of proteins, especially those in cardiomyocytes involved in cardiac excitation-contraction coupling. PKA activity is spatially and temporally regulated through compartmentalization by protein kinase A anchoring proteins.
Lin, Changsong, Guo, Xiaogang, Lange, Stephan, Liu, Jie, Ouyang, Kunfu, Yin, Xiang, Jiang, Liujun, Cai, Yibo, Mu, Yongxin, Sheikh, Farah, Ye, Sheng, Chen, Ju, Ke, Yuehai, Cheng, Hongqiang   +13 more
openaire   +4 more sources

cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages

Frontiers in Microbiology, 2021
We review the role of signaling pathways in regulation of the key processes of merozoite egress and red blood cell invasion by Plasmodium falciparum and, in particular, the importance of the second messengers, cAMP and Ca2+, and cyclic nucleotide ...
Edwin Lasonder, Kunal More, Shailja Singh, Malak Haidar, Malak Haidar, Daniela Bertinetti, Eileen J. Kennedy, Friedrich W. Herberg, Anthony A. Holder, Gordon Langsley, Gordon Langsley, Chetan E. Chitnis   +11 more
doaj   +1 more source