Results 21 to 30 of about 82,113 (260)

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance Dissemination of chemical information throughout the cell is a fundamental biological process with clinical relevance. Pathological changes in local signaling enzyme activity are linked to diseases, including schizophrenia, Alzheimer’s disease, cardiac arrhythmias, and seizures.
F. Donelson Smith, Mitchell H. Omar, Patrick J. Nygren, Joseph Soughayer, Naoto Hoshi, Ho-Tak Lau, Calvin G. Snyder, Tess C. Branon, Debapriya Ghosh, Lorene K. Langeberg, Alice Y. Ting, Luis F. Santana, Shao-En Ong, Manuel F. Navedo, John D. Scott   +14 more
openaire   +4 more sources

A Flagellar A-Kinase Anchoring Protein with Two Amphipathic Helices Forms a Structural Scaffold in the Radial Spoke Complex [PDF]

, 2012
A-kinase anchoring proteins (AKAPs) contain an amphipathic helix (AH) that binds the dimerization and docking (D/D) domain, RIIa, in cAMP-dependent protein kinase A (PKA). Many AKAPs were discovered solely based on the AH–RIIa interaction in vitro.
Alto, Angelo, Banky, Barber, Brokaw, Burns-Hamuro, Cao, Carr, Carr, Carr, Chen, Cho, Diener, Diener, Fujita, Gaillard, Gaillard, Gold, Greengard, Gupta, Habermacher, Habermacher, Herberg, Hirsch, Howard, Hsu, Huang, Jarnaess, Jennifer M. Dienes, Jiang, Kammerer, Kinderman, Kindle, Klauck, Kohno, Li, Martin St. Maurice, Mastronarde, Mauban, Means, Mitchell, Morikis, Newell, Nicastro, Omoto, Patel, Patel-King, Pauling, Pigino, Pinfen Yang, Priyanka Sivadas, Roguev, Rual, Sarma, Satir, Scott, Silflow, South, Wang, Warner, Wei, Welch, William D. Meek, Williams, Wirschell, Witman, Xia, Xu, Yang, Yang, Yang, Yang   +71 more
core   +2 more sources

Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution. [PDF]

, 2017
Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is
Bradley, John E, Espinoza, Celia R, Finley, J Cameron, Hagood, James S, Head, Brian P, Kim, Jeeyeon, Liu, Xiaoqiu, Mah, Emma J, Patel, Hemal H, Shentu, Tzu-Pin, Taype, Carmen A, Wong, Simon S   +11 more
core   +1 more source

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda, Aimanianda, Al-Fattani, Albrecht, Albuquerque, Alvarez, Arroyo, Babady, Baker, Beauvais, Beauvais, Beauvais, Becker, Bonhomme, Bowen, Brown, Bruno, Bulmer, Butler, Cabib, Cabib, Cabib, Cabib, Casadevall, Casadevall, Cassone, Cassone, Castillo, Chaffin, Cheetham, Cho, Coronado, Couto, Crowe, Cushion, Cutler, Cutler, Da Silva, Dadachova, Dadachova, Dague, Dan, De Las Peñas, Del Poeta, DeMarini, Dennehy, Doering, Domer, Douglas, Douglas, Duro, Eisenhaber, Eisenman, Ene, Erwig, Fairlamb, Fernandes, Firon, Fleet, Fontaine, Frieman, Fu, Gagnon-Arsenault, García, García, Gilbert, Glasgow, Gravelat, Gresnigt, Groot, Groot, Groot, Groot, Hall, Hancock, Henry, Herrero, Hiller, Hilpert, Hohl, Hoyer, Hurtado-Guerrero, Ibrahim, Iorio, Irazoqui, Ito, Johnson, Kanetsuna, Karababa, Kaur, Kim, Klis, Klis, Klutts, Kozubowski, Kozubowski, Lamaris, Langfelder, Larsen, Latge, Latgé, Lee, Lee, Lee, Lenardon, Lenardon, Lesage, Levin, Li, Li, Li, Lipschutz, Lombard, Ma, Ma, MacCallum, Machesky, Macho, Martinez, Marty, Martín-Cuadrado, McFadden, Mentlak, Money, Money, Morelle, Morozov, Mouyna, Mouyna, Moyrand, Munro, Munro, Munro, Müller, Netea, Nett, Nobile, Norice, Nosanchuk, Nosanchuk, Odds, Oliveira-Garcia, Oliveira-Garcia, Ostrosky-Zeichner, Paolo, Paris, Park, Perlin, Piotrowski, Pitarch, Popolo, Pérez, Rachini, Rajendran, Rappleye, Rappleye, Rauceo, Reese, Reese, Reese, Reid, Reinoso-Martín, Rispail, Román, Roncero, Rowbottom, Sandini, Schorr, Schuster, Seidl, Selvaggini, Sendid, Shahinian, Sheppard, Sohn, Sorgo, Spellberg, Staab, Steinbach, Steinbach, Steinberg, Steinberg, Stynen, Sudbery, Sundstrom, Sánchez-Vallet, Thompson, Torosantucci, Treitschke, Tsai, Urban, Valdivia, Vargas-Muñiz, Veerdonk, Virag, Wagener, Walker, Walker, Walker, Walton, Weber, Wessels, Wessels, Wheeler, Wheeler, Wiederhold, Wozniak, Wösten, Xin, xSchuster, Yin, Yoneda, Zaragoza, Zarnowski, Zipfel, Zupancic   +215 more
core   +1 more source

Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins [PDF]

, 2014
The invasion of Theileria sporozoites into bovine leukocytes is rapidly followed by the destruction of the surrounding host cell membrane, allowing the parasite to establish its niche within the host cell cytoplasm.
Dobbelaere, D A, Heussler, V T, Von Schubert, C, Wastling, J M, Wiens, O, Woods, K L, Xia, D   +6 more
core   +3 more sources

Crystallization of Adenylylsulfate Reductase from Desulfovibrio gigas: A Strategy Based on Controlled Protein Oligomerization [PDF]

, 2011
Adenylylsulfate reductase (adenosine 5′-phosphosulfate reductase, APS reductase or APSR, E.C.1.8.99.2) catalyzes the conversion of APS to sulfite in dissimilatory sulfate reduction. APSR was isolated and purified directly from massive anaerobically grown
Chan, Sunney I., Chen, Chun-Jung, Chiang, Yuan-Lan, Chuankhayan, Phimonphan, Fang, Jou-Yin, Hsieh, Yin-Cheng, Huang, Yen-Chieh, Liu, Ming-Yih, Wang, Vincent C.-C., Yang, Ming-Chi   +9 more
core   +1 more source

Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence. [PDF]

, 2019
Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products.
Chen, Jin-Gui, DiFazio, Stephen, Dixon, Richard A, Furches, Anna, Gazolla, Joao Gabriel Felipe Machado, Jacobson, Daniel, Jones, Piet, Joubert, Wayne, Kainer, David, Large, Annabel, Macaya-Sanz, David, Martin, Madhavi Z, Ranjan, Priya, Rao, Xiaolan, Romero, Jonathon, Schmutz, Jeremy, Shah, Manesh, Sreedasyam, Avinash, Streich, Jared, Tschaplinski, Timothy J, Tuskan, Gerald A, Walker, Angelica M, Weighill, Deborah, Zhao, Nan   +23 more
core   +3 more sources

A Minimum-Labeling Approach for Reconstructing Protein Networks across Multiple Conditions [PDF]

, 2013
The sheer amounts of biological data that are generated in recent years have driven the development of network analysis tools to facilitate the interpretation and representation of these data.
D. Beisser, E. Lotem, H. Farhan, J. Simpson, M. Hamasaki, N. Ishihara, N. Mizushima, O. Engelhardt, P. Watson, S. Shapira   +9 more
core   +3 more sources

A-kinase anchoring proteins: scaffolding proteins in the heart

American Journal of Physiology-Heart and Circulatory Physiology, 2011
The pleiotropic cyclic nucleotide cAMP is the primary second messenger responsible for autonomic regulation of cardiac inotropy, chronotropy, and lusitropy. Under conditions of prolonged catecholaminergic stimulation, cAMP also contributes to the induction of both cardiac myocyte hypertrophy and apoptosis.
Diviani Dario, Dodge-Kafka Kimberly L, Li Jinliang, Kapiloff Michael S   +3 more
openaire   +3 more sources

An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development [PDF]

, 2007
Proper regulation of receptor tyrosine kinase (RTK)-Ras-mitogen-activated protein kinase (MAPK) signaling pathways is critical for normal development and the prevention of cancer.
Elgort, Marc G., Huang, Jingyu, Jongeward, Gregg, Lauritzen, Amara, Modzelewska, Katarzyna, Moghal, Nadeem, Sternberg, Paul W., Yoon, Charles H.   +7 more
core   +2 more sources