Results 261 to 270 of about 25,315 (294)

Community‐based alcohol counselling: a randomized clinical trial

Addiction, 2002
To examine the effectiveness of a brief intervention (BI) and cognitive behaviour therapy (CBT) for alcohol abuse.A randomized trial with clients randomized within counsellors.Community-based drug and alcohol counselling in Australia.Of all new clients attending counselling.
Shakeshaft, Anthony P., Bowman, Jenny A,, Burrows, Sally, Doran, Christopher M., Sanson-Fisher, Rob W.   +4 more
openaire   +3 more sources

Prophylactic antibiotics in sialendoscopy: a randomized clinical trial

European Archives of Oto-Rhino-Laryngology
Antibiotics have been prescribed routinely in sialendoscopy procedures to reduce the risk of postoperative infection, despite the limited evidence supporting this practice. Being necessary to assess the need for antibiotics in Sialendoscopy, aiming to provide evidence-based guidance to clinicians regarding antibiotic administration in this procedure.A ...
Carlos M, Chiesa-Estomba, Alvaro, Sanchez-Barrueco, Giovanni, Cammaroto, Jerome R, Lechien, Miguel, Mayo-Yanez, Carlos, Cenjor, Pasquale, Capaccio, Carlos, Saga-Gutierrez   +7 more
openaire   +2 more sources

Is the future for clinical trials internet-based? A cluster randomized clinical trial

Clinical Trials, 2005
Objective To compare the efficiency and ease of use of internet data capture compared with conventional paper based data recording in the conduct of a clinical trial. Design Multicentre, cluster randomized clinical trial. Setting General practice in the UK.
Jennifer, Litchfield, Jenny, Freeman, Henrik, Schou, Mark, Elsley, Robert, Fuller, Barrie, Chubb   +5 more
openaire   +2 more sources

A Random Walk Rule for Phase I Clinical Trials

Biometrics, 1997
We describe a family of random walk rules for the sequential allocation of dose levels to patients in a dose-response study, or phase I clinical trial. Patients are sequentially assigned the next higher, same, or next lower dose level according to some probability distribution, which may be determined by ethical considerations as well as the patient's ...
Durham, Stephen D., Flournoy, Nancy, Rosenberger, William F.   +2 more
openaire   +3 more sources

Immunotherapy and recurrent abortion: a randomized clinical trial.

Human reproduction (Oxford, England), 1994
We conducted a randomized trial comparing expectant management versus immunotherapy with paternal leukocytes to improve obstetric outcome in women with unexplained recurrent abortion. Eligible for the study were women with unexplained recurrent abortion (three or more miscarriages and no live birth), negative findings of immunological screening and no ...
M. T. Illeni, G. Marelli, F. Parazzini, B. Acaia, L. Bocciolone, M. Bontempelli, D. Faden, L. Fedele, A. Maffeis, E. Radici   +9 more
openaire   +2 more sources

Sympathicotomy for Isolated Facial Blushing: A Randomized Clinical Trial

The Annals of Thoracic Surgery, 2012
Facial blushing is one of the most peculiar of human expressions. The pathophysiology is unclear, and the prevalence is unknown. Thoracoscopic sympathectomy may cure the symptom and is increasingly used in patients with isolated facial blushing. The evidence base for the optimal level of targeting the sympathetic chain is limited to retrospective case ...
Licht, Peter Bjørn, Pilegaard, Hans K, Ladegaard, Lars   +2 more
openaire   +4 more sources

A Review of Randomized Clinical Trials in Tinnitus

The Laryngoscope, 1999
AbstractObjectives:Review reports of randomized clinical trials (RCTs) in tinnitus to identify well‐established treatments, promising developments, and opportunities for improvement in this area of clinical research.Study Design:Literature review of RCTs (1964‐1998) identified by MEDLINE and OLD MEDLINE searches and personal files.Methods:Studies were ...
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The Basic Structure of a Randomized Clinical Trial

2016
According to the Directive 2001/20/EC of the European Union, a clinical trial is any investigation in human subjects intended to (1) discover or verify the clinical, pharmacological, and/or other pharmacodynamic effects of one or more investigational medicinal product(s), (2) identify any adverse reactions to one or more investigational medicinal ...
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A randomized controlled clinical trial

Journal of Controlled Release, 2022
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The Everyday Function Intervention Trial (EFIT) protocol: A randomized clinical trial

Contemporary Clinical Trials
Preserving cognition and everyday function is essential for maintaining independence and reducing risk of Alzheimer's disease and related dementias (ADRD). Useful Field of View training (UFOVt) is a computerized cognitive training program that achieves these goals; however, the mechanisms underlying UFOVt are unclear. The Everyday Function Intervention
Lesley A, Ross, Courtney, Fine, Abigail T, Stephan, Hye Won, Chai, Ava, McVey, Christine B, Phillips, Alyssa, Gamaldo, Jacqueline, Mogle, Nancy, Dennis, Martin, Sliwinski, Kristina, Visscher   +10 more
openaire   +2 more sources