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Randomized clinical trials: Alternatives to conventional randomization
The American Journal of Emergency Medicine, 1986The randomized allocation format remains an exceedingly powerful tool for clinical research. Because humans are the subjects in clinical research, this area of scientific study must operate within the limits dictated by such basic principles as individual autonomy, justice, and beneficence.
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Composite Randomization Designs for Clinical Trials
Biometrics, 1981This paper proposes a new design for the augmentation of a randomized clinical trial through the participation of private physicians who do not randomize individual patients. Each private physician is randomly assigned a study treatment which he or she uses consistently for all eligible patients. A statistically rigorous method of analysis is described,
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Journal of the American Statistical Association, 2000
(2000). The Randomized Clinical Trial. Journal of the American Statistical Association: Vol. 95, No. 449, pp. 312-315.
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(2000). The Randomized Clinical Trial. Journal of the American Statistical Association: Vol. 95, No. 449, pp. 312-315.
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Why Randomize in Clinical Trials?
Diabetes Care, 1983J, Barbosa, J, Connett, R, Ramsay
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