Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure. [PDF]
OBJECTIVES: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy, and cost-effectiveness of a strategy of adjusting therapy with the goal of achieving and
Adams, Kirkwood F. +15 more
core +3 more sources
Spinal cord stimulation for predominant low back pain in failed back surgery syndrome: study protocol for an international multicenter randomized controlled trial (PROMISE study) [PDF]
Background: Although results of case series support the use of spinal cord stimulation in failed back surgery syndrome patients with predominant low back pain, no confirmatory randomized controlled trial has been undertaken in this patient group to date.
Annemans, Lieven +9 more
core +5 more sources
Investigation of Resonance Effect Caused by Local Exposure of Extremely Low Frequency Magnetic Field on Brain Signals: A Randomize Clinical Trial [PDF]
Background and Objectives: Some studies have investigated the effects of extremely low frequency magnetic fields (ELF-MFs) on brain signals, but only few of them have reported that humans exposed to magnetic fields exhibit changes in brain signals at the
Rasul Zadeh Tabataba’ei K +3 more
doaj +2 more sources
Randomized clinical trials in Clinical Rehabilitation [PDF]
A randomized clinical trial (RCT) is currently the strongest method for evaluating interventions in clinical practice. RCTs also provide the politically most powerful form of evidence. However it is not necessarily agreed what constitutes an RCT. This editorial explores what might be included within the rubric of ‘randomized clinical trial' (and ...
openaire +2 more sources
Glossary for randomized clinical trials [PDF]
AbstractRandomized clinical trials are positioned at the highest level of primary clinical evidence, as they are designed to be unbiased with a reduced risk of systematic error. The Consolidated Standards of Reporting Trials (CONSORT) statement was first developed in 1996 to improve the reporting quality of randomized clinical trials with updates being
V. Nagendrababu +3 more
openaire +2 more sources
Effects of Recitation of Holy Quran on Anxiety of Women before Cesarean Section: A Randomize Clinical Trial [PDF]
Background and Objectives: Anxiety is a kind of agitation and concern stemming from the feeling of threat or hazard in human. It can decrease or increase the understanding ability of individuals.
Ranjbar N, Mir Bagher AjorPaz N
doaj +2 more sources
Comparison of the Effect of the Routine Bowel Preparation and Use of Oral Sodium Phosphate on Acceptance and Bowel Cleansing in Patients Undergoing Colonoscopy: A Randomize Clinical Trial [PDF]
Background and Objectives: Treatment team perform a variety of practices in the fields of treatment and caring. The main domain of nursing practice is to prepare patients for diagnostic tests.
A Ghanbari +4 more
doaj +1 more source
Background Lymph node (LN) metastasis is the most common metastasis route in gastric cancer. Extensive dissection of LNs can significantly improve the prognosis of patients with gastric cancer.
Yanjun Lu +11 more
doaj +1 more source
Randomized experiments ensure robust causal inference that are critical to effective learning analytics research and practice. However, traditional randomized experiments, like A/B tests, are limiting in large scale digital learning environments.
Almirall D +5 more
core +1 more source
A Bayesian adaptive marker‐stratified design for molecularly targeted agents with customized hierarchical modeling [PDF]
It is well known that the treatment effect of a molecularly targeted agent (MTA) may vary dramatically, depending on each patient's biomarker profile. Therefore, for a clinical trial evaluating MTA, it is more reasonable to evaluate its treatment effect ...
Cao, Sha +4 more
core +3 more sources

