Results 91 to 100 of about 1,626,345 (289)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
AVRUPA BİRLİĞİ’NE UYUM SÜRECİNDE TÜRKİYE’DE TELEVİZYON YAYINCILIĞINA YÖNELİK DÜZENLEMELER
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2007 AB, Lizbon Stratejisi ile belirlediği, 2010 yılına kadar dünyanın rekabet gücü en yüksek, dinamik bilgi ekonomisine ulaşma hedefi doğrultusunda yoğun bir teknik altyapıve mevzuat geliştirme faaliyeti ile rakipleri olan ABD ve Japonya’nın önüne geçme ...
Vedat Çakır, Birol Gülnar
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FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Ab Intus, 2022 El mercado de híbridos de maíz para producción de granos ofrece todos los años nuevos materiales, cuyo comportamiento a campo frente a las enfermedades y la adaptación a los diferentes ambientes varía según la zona de producción.
Mónica Silvina Zuza +3 more
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Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Ab Intus, 2022 Se define como probiótico a todo “microorganismo vivo” que cuando es administrado en cantidades adecuadas confiere un beneficio para la salud del huésped.
Alejandra Magnoli +5 more
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FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Ab Intus, 2022 Las infecciones con Mycoplasma spp. están asociadas con diferentes cuadros clínicos en rumiantes: mastitis, neumonía, artritis, otitis, entre otros. Sin embargo, existen escasos reportes de cuadros clínicos asociados con estas infecciones en pequeños ...
German Cantón +7 more
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