Results 71 to 80 of about 46,714 (148)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Mastitis y muerte en una oveja Corriedale asociada a una infección con Mycoplasma spp. en la provincia de Buenos Aires

Ab Intus, 2022
Las infecciones con Mycoplasma spp. están asociadas con diferentes cuadros clínicos en rumiantes: mastitis, neumonía, artritis, otitis, entre otros. Sin embargo, existen escasos reportes de cuadros clínicos asociados con estas infecciones en pequeños ...
German Cantón, María Andrea Fiorentino, Eleonora Lidia Morrell, Valeria Scioli, Facundo Urtizbiría, Juan Ignacio Lobo, Erika Sticotti, Pablo Tamiozzo   +7 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Riesgos ocupacionales en veterinarios dedicados a la producción porcina

Ab Intus, 2022
Los veterinarios están expuestos a numerosos peligros físicos, biológicos y químicos. Los objetivos de este trabajo fueron evaluar la ocurrencia de enfermedades profesionales y accidentes laborales, el uso de elementos de protección personal y la ...
Laura Inés Ugnia †, Juan Carlos Trolliet, Hector Tarabla   +2 more
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Detección molecular de Mycoplasma sp. en el tracto genital de burros domésticos sanos

Ab Intus, 2022
Se han identificado varias especies de Mycoplasma en el tracto reproductivo de los caballos, siendo Mycoplasma equigenitalium (M. equigenitalium) la más prevalente y asociado a fallas reproductivas.
Pablo Tamiozzo, Erika Sticotti, Ana Flores Bragulat, Carolina Alonso, Mauro Macció, Luis Losinno   +5 more
doaj  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Reshaping the European Union Landscape: The Rise of Far-Right Movements and Their Potential Impact on Middle East Policy

İmgelem
The rise of far-right parties within the European Union has raised significant concerns about potential shifts in EU foreign policy, particularly with regard to the Middle East.
Zaoui Rabah
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source