Results 51 to 60 of about 5,035,811 (266)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
First-principles results for electromagnetic properties of $sd$ shell nuclei
, 2017 In this work we present $ab~initio$ shell-model calculations for electric quadrupole moments and magnetic dipole moments of $sd$ shell nuclei using valence-space Hamiltonians derived with two $ab~initio$ approaches: the in-medium similarity ...
Saxena, Archana, Srivastava, Praveen C.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Akademik İncelemeler Dergisi, 2014 1974’te Avrupa Bölgesel Kalkınma Fonlarının oluşturulmasından sonra zaman içerisinde şekillenen AB bölgesel politikaları 1990 sonrasında AB üyeliği için başvuruda bulunan ülkeler için üyelik öncesi uyum sürecinde ilerleme kaydedilmesi gereken ...
Aziz Tuncer, Bilal Eryılmaz
doaj
Erciyes İletişim DergisiMedia ownership concentration threatens media freedom and pluralism by enabling economic and political influence over editorial decisions and information flow.
Canan Özcan, Vedat Çakır
doaj +1 more source
Biomedicines, 2020 Amyloid precursor protein (APP) is directly related to Aβ amyloidosis—a hallmark of Alzheimer’s disease (AD). However, the impact of environmental factors upon APP biology and Aβ amyloid pathology have not been well studied.
Xiaoyang Mou +6 more
doaj +1 more source
Quantum coherence of the molecular states and their corresponding currents in nanoscale Aharonov-Bohm interferometers [PDF]
, 2016 By considering a nanoscale Aharonov-Bohm (AB) interferometer containing a parrallel-coupled double dot coupled to the source and drain electrodes, we investigate the AB phase oscillations of transport current via the bonding and antibonding state ...
Liu, Jian-Heng +2 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Kitap Tanıtımı: Brexit Sonrası Birleşik Krallık ve AB'nin Geleceği
Ekonomi, Politika & Finans Araştırmaları Dergisi, 2017 Diğer Avrupa devletlerinin aksine vetolu ve sıkıntılı bir dönemin ardından Avrupa Birliğine giren İngiltere’nin 2016 yılında aldığı “Brexit” kararı, şüphesiz sadece İngiltere’de değil tüm Avrupa’da dengeleri değiştirecek bir olaylar zincirinin ...
Yusuf Ertuğral
doaj