Results 121 to 130 of about 26,674 (238)

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Circulating Th17.1 cells as candidate for the prediction of therapeutic response to abatacept in patients with rheumatoid arthritis: An exploratory research.

PLoS ONE, 2019
T-helper (Th)17.1 cells exhibit high pathogenicity in inflammatory diseases. This study aimed to identify the changes in the proportions of Th subsets, including Th17.1, which are associated with abatacept treatment response in Japanese patients with ...
Shinji Maeda, Satoshi Osaga, Tomoyo Maeda, Norihisa Takeda, Shin-Ya Tamechika, Taio Naniwa, Akio Niimi   +6 more
doaj   +1 more source

Rheumatoid arthritis and spondyloarthropathy [PDF]

, 2013
Part 2 of the article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/13280Rheumatoid arthritis (RA) and spondyloarthropathy are two groups of inflammatory joint disease.
Vassallo, Pierre
core  

Clinical features and comorbidity patterns in early and very early rheumatoid arthritis: Insights from a China nationwide survey

Rheumatology &Autoimmunity, EarlyView.
Haojie Xu, Liyun Zhang, Yuehong Huo, Rui Wu, Lijun Wu, Ling Lei, Linyu Geng, Chunyu Tan, Xiaomei Li, Ru Li, Yin Su, the Women's Rheumatoid Arthritis Research Collaborative Group   +11 more
wiley   +1 more source

Model‐Based Meta‐Analysis With MonolixSuite: A Tutorial for Longitudinal Categorical and Continuous Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Model‐based meta‐analysis (MBMA) informs key drug development decisions by integrating data, published or unpublished, from multiple studies. Due to these various sources of information and the use of summary‐level data (e.g., mean responses over treatment arms or percent responders), MBMA models require careful implementation.
Chloe Bracis, Amit Taneja, Yassine Kamal Lyauk, Heather Barcomb, Amparo de la Peña, Géraldine Cellière   +5 more
wiley   +1 more source

RAISE – Rheumatoid Arthritis Independent Swiss Treatment Expectations and Outcome: results for the abatacept subpopulation

Swiss Medical Weekly, 2013
QUESTIONS UNDER STUDY: Clinical trials do not necessarily reflect the results obtained in daily clinical practice. By conducting a non-interventional, observational study with biologics in rheumatoid arthritis (RA) patients in Switzerland, we aimed ...
Jean Dudler, Roland Tuerk, Thomas Handschin, Adrian Forster   +3 more
doaj   +1 more source

Abatacept reduces levels of switched memory B cells, autoantobodies, and immunoglobulins in patients with Rheumatoid Arthritis [PDF]

, 2014
Objective. Abatacept (ABA) is a chimeric molecule, able to block the CD28-mediated costimulatory pathway. To evaluate the hypothesis that, through this mechanism of action, ABA may down-modulate the immune responses of B lymphocytes in rheumatoid ...
A.PEDRINI, A.TINCANI, D.RICOTTA, L.CAIMI, L.PAOLINI, M.SCARSI, P.AIRO’, S.PIANTONI   +7 more
core  

Patient-reported outcome assessment of inflammatory arthritis patient experience with intravenously administered biologic therapy [PDF]

, 2017
Objective: To evaluate patient perspectives regarding utilization of intravenous (IV) therapy for inflammatory arthritis (IA). Methods: This was a single-center, non-interventional, patient questionnaire-based study of adult IA patients currently ...
Black, Shawn, DeHoratius, Raphael J., Gaylis, Norman B., Kafka, Wesley A., Parenti, Dennis, Sagliani, Joanne, Tang, Kezhen L.   +6 more
core   +3 more sources

Rheumatoid Arthritis Preceded by Interstitial Lung Disease Controlled by Long‐Term Treatment With the Janus Kinase 1‐Selective Inhibitor, Filgotinib: A Case Report

Respirology Case Reports, Volume 14, Issue 2, February 2026.
We present a case of ILD preceding RA onset. The disease activity of arthritis and ILD was controlled, and ILD was stabilised for 4 years with the JAK1 selective inhibitor, filgotinib. ABSTRACT We present a case of active interstitial lung disease (ILD) preceding the onset of rheumatoid arthritis (RA).
Takeo Sato, Shoko Nakazawa, Shotaro Yamamoto, Katsuya Nagatani, Kojiro Sato   +4 more
wiley   +1 more source

Impact of concomitant methotrexate on disease activity in patients with rheumatoid arthritis tapering abatacept: results from KOBIO registry

Frontiers in Medicine
ObjectivesTapering biologic agents can be considered for patients with stable disease activity in rheumatoid arthritis (RA). However, the specific strategy for abatacept is uncertain.
Jun Won Park, Ju Yeon Kim, Min Jung Kim, Yoo Kyoung Lim, Hyoun-Ah Kim, Jin Hyun Kim, Kichul Shin, Kichul Shin   +7 more
doaj   +1 more source