Results 161 to 170 of about 53,560 (304)

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr   +10 more
wiley   +1 more source

Risk factors for Taenia saginata cysticercus infection in cattle in the United Kingdom: a farm-level case-control study and assessment of the role of movement history, age and sex [PDF]

open access: yes, 2016
Abuseir   +23 more
core   +2 more sources

A Farewell to Arms… Manufacturing: Learning From a Landmine Producer Who Became a Deminer

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Certain industries—labeled “dirty,” “sinful,” “stigmatized,” or “controversial”—are under public scrutiny because of the ethical, social, and environmental concerns that they raise. Previous research has typically focused on the industry or organizational level of analysis, examining how companies in controversial industries can enhance their ...
Marco Guerci, Luca Carollo
wiley   +1 more source

Comparative developmental competence and gene expression in laparoscopically retrieved- and abattoir-derived goat oocytes. [PDF]

open access: yesFront Vet Sci
Malik AA   +12 more
europepmc   +1 more source

Chironomid‐based summer temperature reconstruction of the Eemian–Weichselian transition at Lichtenberg, northern Germany

open access: yesBoreas, EarlyView.
Understanding the temperature variability of past interglacial cycles is essential to predict future climates. We present a new summer temperature reconstruction, based on the subfossil chironomid record from a small palaeolake adjacent to the Middle Palaeolithic site of Lichtenberg, northern Germany. The record spans from the Saalian late glacial over
Sonja Rigterink   +10 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz   +8 more
wiley   +1 more source

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