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Drug resistance updates, 2022 Multidrug resistance (MDR) is the phenomenon in which cancer cells simultaneously develop resistance to a broad spectrum of structurally and mechanistically unrelated drugs. MDR severely hinders the effective treatment of cancer and is the major cause of
Jingyi Fan +3 more
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Structural and Mechanistic Principles of ABC Transporters.
Annual Review of Biochemistry, 2020 ATP-binding cassette (ABC) transporters constitute one of the largest and most ancient protein superfamilies found in all living organisms. They function as molecular machines by coupling ATP binding, hydrolysis, and phosphate release to translocation of
C. Thomas, R. Tampé
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Application of activity - based costing in companies in Poland [PDF]
, 2010 Findings of the research have both practical and theoretical implications. First, from the practical point of view, future implementers of ABC systems should be aware of factors actually influencing ABC implementation as well as problems which can be ...
Wnuk-Pel, Tomasz
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JACC: Asia, 2023 ABCs offers an analysis of two Corsican alphabet books. The first text is a monolingual Corsican alphabet book accompanied by illustrations and aimed at early-age readers. The second is a bilingual French-Corsican photo project authored by the students from the previous chapter.
Saket Sanghai, Charles A. Henrikson
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Simulation-Based Cost Evaluation of Maritime Transportation
Journal of Eta Maritime Science, 2023 In a globalized world, maritime transportation is a crucial component for both producers and consumers. In this sector, where 10 billion tons of freight are moved each year, both shippers and carriers grapple with financial obligations.
Davut Pehlivan, Kadir Çiçek
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Bulletin of the London Mathematical Society, 2016 We give an overview of recent developments in the theory of dimer models. The viewpoint we take is inspired by mirror symmetry. After an introduction to the combinatorics of dimer models, we will first look at dimers in dynamical systems and statistical mechanics, which can be viewed as coming from the A-model in mirror symmetry.
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ABC of Content Validation and Content Validity Index Calculation
Education in Medicine Journal, 2019 There are five sources of validity evidence that are content, response process, internal structure, relation to other variables, and consequences. Content validity is the extent of a measurement tool represents the measured construct and it is considered
M. Yusoff
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Postgraduate Medical Journal, 2000 ABC of Rheumatology. 2nd Ed. Edited by Michael L Snaith. (Pp 90; £16.95 paperback.) BMJ Publishing Group, 1999. ISBN 0-7279-1385-9. ABC of Rheumatology was based on the excellent series published in the BMJ . This is the second edition of the book, which continues the successful formula of combining chapters dealing with common rheumatic disorders ...
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Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance
Nature Communications, 2021 Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem.
Emily L. Giddings +24 more
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Revista Conjuntura Austral, 2015 This article aims to analyze the international cooperation provided by Brazil through the Brazilian Cooperation Agency (ABC) and the Ministry of Social Development and Fight against Hunger (MDS) during the Lula government (2003-2010).
Luciana Pazini Papi, Klei Medeiros
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