Results 61 to 70 of about 1,296,858 (303)

3rd ESO-ESMO international consensus guidelines for Advanced Breast Cancer (ABC 3).

Breast, 2017
• This ESO-ESMO ABC 5 Clinical Practice Guideline provides key recommendations for managing advanced breast cancer patients. • It provides updates on managing patients with all breast cancer subtypes, LABC, follow-up, palliative and supportive care ...
F. Cardoso, A. Costa, E. Senkus, M. Aapro, F. André, C. Barrios, J. Bergh, G. Bhattacharyya, L. Biganzoli, M. Cardoso, L. Carey, D. Corneliussen-James, G. Curigliano, V. Diéras, N. Saghir, A. Eniu, L. Fallowfield, D. Fenech, P. Francis, K. Gelmon, A. Gennari, N. Harbeck, C. Hudis, B. Kaufman, I. Krop, M. Mayer, H. Meijer, S. Mertz, S. Ohno, O. Pagani, E. Papadopoulos, F. Peccatori, F. Penault-Llorca, M. Piccart, J. Pierga, H. Rugo, L. Shockney, G. Sledge, S. Swain, C. Thomssen, A. Tutt, D. Vorobiof, Bing-he Xu, L. Norton, Eric P. Winer   +44 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

LLL & ABC

Journal of Number Theory, 2004
This note is an observation that the LLL algorithm applied to prime powers can be used to find "good" examples for the ABC and Szpiro conjectures.
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Key Factors of Effectiveness of Developing an Activity Based Cost Accounting and Analysis System at an Enterprise

Учёт. Анализ. Аудит, 2019
The article researches the problems related to the improvement of the efficiency of developing a system of activity based cost accounting and analysis at an enterprise based on a number of important factors.
Y. V. Trifonov, A. N. Vizgunov
doaj   +1 more source

ABC-CNN: An Attention Based Convolutional Neural Network for Visual Question Answering [PDF]

, 2016
We propose a novel attention based deep learning architecture for visual question answering task (VQA). Given an image and an image related natural language question, VQA generates the natural language answer for the question.
Chen, Kan, Chen, Liang-Chieh, Gao, Haoyuan, Nevatia, Ram, Wang, Jiang, Xu, Wei   +5 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Implementing an activity-based costing system: A case study based on Platform Plus Limited [PDF]

, 2018
This research aimed at studying the business process of “Platform Plus Limited” (PPL) and providing recommendations to implement Activity Based Costing (ABC) into the company. The research was focused on understanding the business process of the service ‘
Arachchige, Rushan, Attanayake, Lakshan
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source