Revisión de las características de los transportadores ABC involucrados en patogénesis fúngica
Los transportadores ABC son proteínas con una amplia distribución entre los organismos procariontes y eucariontes; exhiben un mecanismo de transporte dependiente de energía, ya que necesitan de la unión e hidrólisis del ATP para realizar su
Yeny Lizzet Couoh-Uicab +1 more
doaj
Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology [PDF]
AIM: To evaluate ATP-binding cassette (ABC) transporters in colonic pathophysiology as they had recently been related to colorectal cancer (CRC) development.
Andersen, Vibeke +6 more
core +5 more sources
Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke +3 more
wiley +1 more source
Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter [PDF]
Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects.
Brunak, Søren +8 more
core +3 more sources
From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley +1 more source
Revisiting strategies to target ABC transporter-mediated drug resistance in CNS cancer
A significant number of anticancer drugs fail to treat primary and metastatic brain tumors primarily because of the complex blood-brain barrier (BBB) and overexpression of ATP-binding cassette (ABC) transporters, which decrease drug penetration into the ...
Haneen Amawi +9 more
doaj +1 more source
Expression of some ATP-binding cassette transporters in acute myeloid leukemia
Hematopoietic cells express ATP binding cassette (ABC) transporters in relation to different degrees of differentiation. One of the known multidrug resistance mechanisms in acute myeloid leukemia (AML) is the overexpression of efflux pumps belonging to ...
Antonella Maria Salvia +8 more
doaj +1 more source
An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein [PDF]
Campylobacter jejuni is a Gram-negative food-borne pathogen associated with gastroenteritis in humans as well as cases of the autoimmune disease Guillain Barre syndrome. C.
Altekruse +61 more
core +1 more source
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
wiley +1 more source
Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. [PDF]
This is a report on the CNS barrier congress held in London, UK, March 22-23rd 2017 and sponsored by Kisaco Research Ltd. The two 1-day sessions were chaired by John Greenwood and Margareta Hammarlund-Udenaes, respectively, and each session ended with a ...
A Brenn +28 more
core +9 more sources

