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Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects [PDF]
BMC GenomicsBackground The ABC (ATP-binding cassette) transporter family constitutes one of the most extensive transmembrane transporter gene families found across all realms of life. In insects, ABC transporters are crucial for processes such as nutrient metabolism,
Wenbin Liu +7 more
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FEBS Letters, 2006 ABC transporters are proteins that are involved in the uptake of nutrients and excretion of harmful substances in biological cells. Defects in human ABC transporters can result in severe diseases. Too high ABC transporter activity can lead to non-responsiveness of cancercells to chemotherapy, and resistance of bacteria to antibiotics.
Flügge, U.I., van Meer, G.
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The role of ABC transporter DrrABC in the export of PDIM in Mycobacterium tuberculosis [PDF]
The Cell SurfaceThe Mycobacterium tuberculosis virulence lipid phthiocerol dimycocerosate (PDIM) is exported by a complex mechanism that involves multiple proteins including the Resistance-Nodulation-Division (RND) transporter MmpL7 and the lipoprotein LppX.
Nabiela Moolla +5 more
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Frontiers in Ecology and Evolution, 2022 While differences in the methylation patterns of ABC transporters under different environmental conditions and their role in plant growth, development, and response to biotic and abiotic stresses are well documented, less is known about the variation in ...
Ambreen Tahir Shah +4 more
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Peroxisomal ABC transporters [PDF]
FEBS Letters, 2006 Peroxisomes perform a range of different functions, dependent upon organism, tissue type, developmental stage or environmental conditions, many of which are connected with lipid metabolism. This review summarises recent research on ATP binding cassette (ABC) transporters of the peroxisomal membrane (ABC subfamily D) and their roles in plants, fungi and
Theodoulou, F. L. +2 more
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Pharmaceutics, 2023 Background: ATP-binding cassette (ABC) transporters comprise a superfamily of genes encoding membrane proteins with nucleotide-binding domains (NBD).
Wandong Zhang +9 more
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Thermodynamics of ABC transporters [PDF]
Protein & Cell, 2015 ABC transporters form the largest of all transporter families, and their structural study has made tremendous progress over recent years. However, despite such advances, the precise mechanisms that determine the energy-coupling between ATP hydrolysis and the conformational changes following substrate binding remain to be elucidated.
Xuejun C. Zhang, Lei Han, Yan Zhao
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Nucleotide-Binding Sites of the Heterodimeric LmrCD ABC-Multidrug Transporter of Lactococcus lactis Are Asymmetric [PDF]
, 2006 LmrCD is a lactococcal, heterodimeric multidrug transporter, which belongs to the ABC superfamily. It consists of two half-transporters, LmrC and LmrD, that are necessary and sufficient for drug extrusion and ATP hydrolysis.
Driessen, Arnold J.M., +3 more
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Circular and L50-like leaderless enterocins share a common ABC-transporter immunity gene
BMC Genomics, 2023 Microbes live within complex communities of interacting populations, either free-living in waters and soils or symbionts of animals and plants. Their interactions include the production of antimicrobial peptides (bacteriocins) to antagonize competitors ...
Claudia Teso-Pérez +5 more
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Enterocin Cross-Resistance Mediated by ABC Transport Systems
Microorganisms, 2021 In their struggle for life, bacteria frequently produce antagonistic substances against competitors. Antimicrobial peptides produced by bacteria (known as bacteriocins) are active against other bacteria, but harmless to their producer due to an ...
Claudia Teso-Pérez +6 more
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