Results 1 to 10 of about 81,965 (299)

ABC-B transporter genes in Dirofilaria immitis

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the mosquito transmission season.
Catherine Bourguinat, Hua Che, Thangadurai Mani, Kathy Keller, Roger K. Prichard   +4 more
doaj   +2 more sources

Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background [PDF]

Frontiers in Pharmacology, 2019
Mutations in ATP Binding Cassette (ABC)-transporter genes can have major effects on the bioavailability and toxicity of the drugs that are ABC-transporter substrates.
Artem Sokolov, Stephanie Ashenden, Stephanie Ashenden, Nil Sahin, Nil Sahin, Richard Lewis, Nurdan Erdem, Elif Ozaltan, Andreas Bender, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Murat Cokol, Murat Cokol, Murat Cokol, Murat Cokol   +15 more
doaj   +3 more sources

Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects [PDF]

BMC Genomics
Background The ABC (ATP-binding cassette) transporter family constitutes one of the most extensive transmembrane transporter gene families found across all realms of life. In insects, ABC transporters are crucial for processes such as nutrient metabolism,
Wenbin Liu, Anmo Zhou, Ziming Shao, Jiaxin Nie, Xinyu Ge, Chuncai Yan, Shaobo Gao, Yiwen Wang   +7 more
doaj   +2 more sources

Export of recombinant proteins in Escherichia coli using ABC transporter with an attached lipase ABC transporter recognition domain (LARD) [PDF]

Microbial Cell Factories, 2009
Background ATP binding cassette (ABC) transporter secretes the protein through inner and outer membranes simultaneously in gram negative bacteria. Thermostable lipase (TliA) of Pseudomonas fluorescens SIK W1 is secreted through the ABC transporter.
Moon Yuseok, Kim Kyeongyeon, You Jinsun, Chung Chan, Kim Hoeon, Ahn Jung   +5 more
doaj   +2 more sources

A twist in the ABC: regulation of ABC transporter trafficking and transport by FK506‐binding proteins [PDF]

FEBS Letters, 2020
Post-transcriptional regulation of ATP-binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination.
Geisler, Markus, Hegedűs, Tamás
core   +5 more sources

ABC Transporters [PDF]

FEBS Letters, 2006
ABC transporters are proteins that are involved in the uptake of nutrients and excretion of harmful substances in biological cells. Defects in human ABC transporters can result in severe diseases. Too high ABC transporter activity can lead to non-responsiveness of cancercells to chemotherapy, and resistance of bacteria to antibiotics.
Flügge, U.I., van Meer, G.
  +8 more sources

Polymorphism in ABC transporter genes of Dirofilaria immitis

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Dirofilaria immitis, a filarial nematode, causes dirofilariasis in dogs, cats and occasionally in humans. Prevention of the disease has been mainly by monthly use of the macrocyclic lactone (ML) endectocides during the mosquito transmission season ...
Thangadurai Mani, Catherine Bourguinat, Roger K. Prichard   +2 more
doaj   +2 more sources

The role of ABC transporter DrrABC in the export of PDIM in Mycobacterium tuberculosis [PDF]

The Cell Surface
The Mycobacterium tuberculosis virulence lipid phthiocerol dimycocerosate (PDIM) is exported by a complex mechanism that involves multiple proteins including the Resistance-Nodulation-Division (RND) transporter MmpL7 and the lipoprotein LppX.
Nabiela Moolla, Helen Weaver, Rebeca Bailo, Albel Singh, Vassiliy N. Bavro, Apoorva Bhatt   +5 more
doaj   +2 more sources

DNA Methylation of ABC Transporters Differs in Native and Non-native Populations of Conyza canadensis L.

Frontiers in Ecology and Evolution, 2022
While differences in the methylation patterns of ABC transporters under different environmental conditions and their role in plant growth, development, and response to biotic and abiotic stresses are well documented, less is known about the variation in ...
Ambreen Tahir Shah, Ambreen Tahir Shah, Zafar A. Reshi, Mohammad Altaf, Mohammad Altaf   +4 more
doaj   +1 more source

Peroxisomal ABC transporters [PDF]

FEBS Letters, 2006
Peroxisomes perform a range of different functions, dependent upon organism, tissue type, developmental stage or environmental conditions, many of which are connected with lipid metabolism. This review summarises recent research on ATP binding cassette (ABC) transporters of the peroxisomal membrane (ABC subfamily D) and their roles in plants, fungi and
Theodoulou, F. L., Holdsworth, M., Baker, A.   +2 more
openaire   +2 more sources