Results 1 to 10 of about 285,749 (186)

Revisión de las características de los transportadores ABC involucrados en patogénesis fúngica

Tecnociencia Chihuahua, 2020
Los transportadores ABC son proteínas con una amplia distribución entre los organismos procariontes y eucariontes; exhiben un mecanismo de transporte dependiente de energía, ya que necesitan de la unión e hidrólisis del ATP para realizar su
Yeny Lizzet Couoh-Uicab, Blondy Beatriz Canto-Canché   +1 more
doaj  

Transcriptome-wide identification and expression analyses of ABC transporters in dwarf polish wheat under metal stresses

Biologia Plantarum, 2017
ABC transporters, which comprise one of the largest protein families, are involved in maintaining osmotic homeostasis, nutrient uptake, pathogen resistance, and metal tolerance.
X. Wang, C. Wang, H. Sheng, Y. Wang, J. Zeng, H. Kang, X. Fan, L. Sha, H. Zhang, Y. Zhou   +9 more
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Revisiting strategies to target ABC transporter-mediated drug resistance in CNS cancer

Cancer Biology & Medicine
A significant number of anticancer drugs fail to treat primary and metastatic brain tumors primarily because of the complex blood-brain barrier (BBB) and overexpression of ATP-binding cassette (ABC) transporters, which decrease drug penetration into the ...
Haneen Amawi, Alaa M. Hammad, F. Scott Hall, Noor Hussein, Aseel O. Rataan, Abeer Mrayyan, Taqwa Al-kofahi, Ali Hmedat, Charles R. Ashby, Amit K. Tiwari   +9 more
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Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum

BMC Genomics, 2013
Background The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. Most are integral membrane proteins that transport a broad spectrum of substrates across
Broehan Gunnar, Kroeger Tobias, Lorenzen Marcé, Merzendorfer Hans   +3 more
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Expression of some ATP-binding cassette transporters in acute myeloid leukemia

Hematology Reports, 2017
Hematopoietic cells express ATP binding cassette (ABC) transporters in relation to different degrees of differentiation. One of the known multidrug resistance mechanisms in acute myeloid leukemia (AML) is the overexpression of efflux pumps belonging to ...
Antonella Maria Salvia, Flavia Cuviello, Sabrina Coluzzi, Roberta Nuccorini, Immacolata Attolico, Sara Pasquina Pascale, Faustino Bisaccia, Michele Pizzuti, Angela Ostuni   +8 more
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The ATP Binding Cassette (ABC) Transporter Gene Family in Lotus (Nelumbo Adans.): Genome-Wide Survey, Characterization and Gene Expression Profile

Biology
ABC transporters (ATP-binding cassette transporters) constitute one of the largest known protein families and are widely distributed in plants. Their primary function involves utilizing energy derived from ATP hydrolysis to transport substrates across ...
Yumeng Zhao, Lijie Cui, Qingqing Liu, Jingjing Huo, Houchen Zhang, Dasheng Zhang, Hong Zhang   +6 more
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Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects

BMC Genomics
Background The ABC (ATP-binding cassette) transporter family constitutes one of the most extensive transmembrane transporter gene families found across all realms of life. In insects, ABC transporters are crucial for processes such as nutrient metabolism,
Wenbin Liu, Anmo Zhou, Ziming Shao, Jiaxin Nie, Xinyu Ge, Chuncai Yan, Shaobo Gao, Yiwen Wang   +7 more
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Enhancing of cerebral Abeta clearance by modulation of ABC transporter expression: a review of experimental approaches

Frontiers in Aging Neuroscience
Clearance of amyloid-beta (Aβ) from the brain is impaired in both early-onset and late-onset Alzheimer’s disease (AD). Mechanisms for clearing cerebral Aβ include proteolytic degradation, antibody-mediated clearance, blood brain barrier and blood ...
David A. Loeffler
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The Methods to Overcome ATP-binding Cassette Transporters-mediated Multi-drug Resistance

مجله دانشکده پزشکی اصفهان, 2013
Background: Multi-drug resistance (MDR) is a prevalent phenomenon occurred in tumor cells in response to chemotherapy. The main cause of MDR is the efflux of drugs by ATP-binding Cassette (ABC) transporters.
Mansoureh Entezar-e-Ghaem, Soheila Rahgozar, Ali Reza Moafi   +2 more
doaj  

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta. [PDF]

Clin Pharmacol Ther
Jung EM, Ieronimakis N, Mousa B, Sheikh ED, Ligon SE, Monson JW, Damicis JR, Kinsman HJ, Bettridge LE, Arnold SLM, Kelly EJ, Unadkat JD, Wang J.   +12 more
europepmc   +1 more source