Results 11 to 20 of about 111,036 (294)
Thermodynamics of ABC transporters [PDF]
Protein & Cell, 2015 ABC transporters form the largest of all transporter families, and their structural study has made tremendous progress over recent years. However, despite such advances, the precise mechanisms that determine the energy-coupling between ATP hydrolysis and
Xuejun C. Zhang, Lei Han, Yan Zhao
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FEBS Letters, 2006 ABC transporters are proteins that are involved in the uptake of nutrients and excretion of harmful substances in biological cells. Defects in human ABC transporters can result in severe diseases. Too high ABC transporter activity can lead to non-responsiveness of cancercells to chemotherapy, and resistance of bacteria to antibiotics.
Flügge, U.I., van Meer, G.
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Peroxisomal ABC transporters [PDF]
FEBS Letters, 2006 Peroxisomes perform a range of different functions, dependent upon organism, tissue type, developmental stage or environmental conditions, many of which are connected with lipid metabolism. This review summarises recent research on ATP binding cassette (ABC) transporters of the peroxisomal membrane (ABC subfamily D) and their roles in plants, fungi and
Theodoulou, F. L. +2 more
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Aberrant DNA Methylation of ABC Transporters in Cancer
Cells, 2020 ATP-binding cassette (ABC) transporters play a crucial role in multidrug resistance (MDR) of cancers. They function as efflux pumps, resulting in limited effectiveness or even failure of therapy.
Katja Zappe, Margit Cichna-Markl
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Current Issues in Molecular Biology, 2022 ATP-binding cassette (ABC) transporters play an important role in driving the exchange of multiple molecules across cell membranes. The plant ABC transporter family is among the largest protein families, and recent progress has advanced our understanding
Xiaoping Gong, Shanhong Wang
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Cells, 2021 The ATP-binding cassette (ABC) transporter superfamily consists of several proteins with a wide repertoire of functions. Under physiological conditions, ABC transporters are involved in cellular trafficking of hormones, lipids, ions, xenobiotics, and ...
Massimo Serra +6 more
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Plants, 2020 The multi-antimicrobial extrusion (MATE), ATP-binding cassette (ABC), and major facilitator superfamily (MFS) are the main plant transporters families, playing an essential role in the membrane-trafficking network and plant-defense mechanism.
Maria H. M. Julião +3 more
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Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype
Frontiers in Pharmacology, 2021 ATP-binding cassette (ABC) drug efflux transporters could contribute to low intracellular concentrations of antiretroviral drugs in HIV-1 cell reservoirs and sanctuary sites.
Sana-Kay Whyte-Allman +2 more
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Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato.
PLoS ONE, 2018 ATP binding cassette (ABC) transporters are proteins that actively mediate the transport of a wide range of molecules, such as organic acids, metal ions, phytohormones and secondary metabolites.
Peter Amoako Ofori +9 more
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Structural basis for the mechanism of ABC transporters. [PDF]
, 2015 The ATP-binding cassette (ABC) transporters are primary transporters that couple the energy stored in adenosine triphosphate (ATP) to the movement of molecules across the membrane.
Beis, K
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