Results 11 to 20 of about 68,283 (287)
Peroxisomal ABC transporters [PDF]
FEBS Letters, 2006 Peroxisomes perform a range of different functions, dependent upon organism, tissue type, developmental stage or environmental conditions, many of which are connected with lipid metabolism. This review summarises recent research on ATP binding cassette (ABC) transporters of the peroxisomal membrane (ABC subfamily D) and their roles in plants, fungi and
Theodoulou, F. L. +2 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 2000 The ATP binding cassette (ABC) superfamily is a large, ubiquitous and diverse group of proteins, most of which mediate transport across biological membranes. ABC transporters have been shown to function not only as ATP-dependent pumps, but also as ion channels and channel regulators.
Theodoulou, Frederica L. +1 more
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The Arabidopsis Book, 2011 ABC transporters constitute one of the largest protein families found in all living organisms. ABC transporters are driven by ATP hydrolysis and can act as exporters as well as importers. The plant genome encodes for more than 100 ABC transporters, largely exceeding that of other organisms.
Joohyun Kang +6 more
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ABC Transporters in Human Diseases [PDF]
, 2022 Mammalian ATP-binding cassette (ABC) transporters constitute a superfamily of proteins involved in many essential cellular processes. Most of these transporters are transmembrane proteins and allow the active transport of solutes, small molecules, and ...
core +1 more source
Microorganisms, 2021 ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as ...
Jeanine Rismondo, Lisa Maria Schulz
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Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters. [PDF]
PLoS ONE, 2011 An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body.
Irina V Lebedeva +2 more
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The impact of ATP-binding cassette transporters on metabolic diseases
Nutrition & Metabolism, 2020 Currently, many people worldwide suffer from metabolic diseases caused by heredity and external factors, such as diet. One of the symptoms of metabolic diseases is abnormal lipid metabolism.
Zixiang Ye, Yifei Lu, Tao Wu
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Aberrant DNA Methylation of ABC Transporters in Cancer
Cells, 2020 ATP-binding cassette (ABC) transporters play a crucial role in multidrug resistance (MDR) of cancers. They function as efflux pumps, resulting in limited effectiveness or even failure of therapy.
Katja Zappe, Margit Cichna-Markl
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Cells, 2021 The ATP-binding cassette (ABC) transporter superfamily consists of several proteins with a wide repertoire of functions. Under physiological conditions, ABC transporters are involved in cellular trafficking of hormones, lipids, ions, xenobiotics, and ...
Massimo Serra +6 more
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Current Issues in Molecular Biology, 2022 ATP-binding cassette (ABC) transporters play an important role in driving the exchange of multiple molecules across cell membranes. The plant ABC transporter family is among the largest protein families, and recent progress has advanced our understanding
Xiaoping Gong, Shanhong Wang
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