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Peroxisomal ABC Transporters: An Update [PDF]
International Journal of Molecular Sciences, 2021 ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of conserved proteins from bacteria to mammals. In humans, three members of this family are expressed in the peroxisomal membrane and belong to the subfamily D: ABCD1 (ALDP), ABCD2 (ALDRP), and ABCD3 (PMP70).
Tawbeh, Ali +3 more
openaire +2 more sources
Plant peroxisomal ABC transporters: flexible and unusual [PDF]
, 2014 ABC transporters of subfamily D mediate import of substrates for β-oxidation into peroxisomes. Whilst mammals possess three peroxisomal ABCD proteins which homodimerise to form transporters with distinct substrate specificities, Baker’s yeast has a ...
Baldwin, J. M. +7 more
core +1 more source
Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family [PDF]
, 2008 Wagner H, Morgenstern B, Dress A. Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family. Algorithms for Molecular Biology.
Andreas Dress +8 more
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A-subclass ATP-binding cassette proteins in brain lipid homeostasis and neurodegeneration
Frontiers in Psychiatry, 2012 The A-subclass of ATP-binding cassette (ABC) transporters comprises twelve structurally related members of the evolutionarily highly conserved superfamily of ABC transporters.
Armin P. Piehler +3 more
doaj +1 more source
Current advances on ABC drug transporters in fish [PDF]
, 2014 Most members of the large ATP-binding cassette (ABC) gene family are transporters involved in substrate translocation across biological membranes. In eukaryotes, ABC proteins functioning as drug transporters are located in the plasma membrane and mediate
Sturm, Armin +2 more
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The effect of silymarin on expression of selected ABC transporters in the rat
Veterinární Medicína, 2011 Silymarin (standardized extract from the seeds of the Silybum marianum) has been used in the supportive therapy of liver diseases and its cytoprotective activity is believed to be based on antioxidant properties.
R. Vecera +4 more
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Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance [PDF]
, 2011 Peroxisomes are indispensable organelles in higher eukaryotes. They are essential for a number of important metabolic pathways, including fatty acid α- and β-oxidation, and biosynthesis of etherphospholipids and bile acids.
Kemp, S. +8 more
core +1 more source
BMC Genomics, 2021 Background ATP-binding cassette (ABC) transporters have been found to play important roles in metabolic transport in plant cells, influencing subcellular compartmentalisation and tissue distribution of these metabolic compounds. Salvia miltiorrhiza Bunge,
Li Yan +3 more
doaj +1 more source
A twist in the ABC: regulation of ABC transporter trafficking and transport by FK506‐binding proteins [PDF]
FEBS Letters, 2020 Post‐transcriptional regulation of ATP‐binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination. Yet, recent accumulating evidence implicates FK506‐binding proteins (FKBPs), a type of peptidylprolyl cis–trans isomerase (PPIase) proteins, in ABC transporter regulation. In this perspective
Markus Geisler, Tamás Hegedűs
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ATP-binding cassette (ABC) transporters in normal and pathological lung
Respiratory Research, 2005 ATP-binding cassette (ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner.
Timmer-Bosscha Hetty +5 more
doaj +1 more source