Results 21 to 30 of about 68,283 (287)

Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype

Frontiers in Pharmacology, 2021
ATP-binding cassette (ABC) drug efflux transporters could contribute to low intracellular concentrations of antiretroviral drugs in HIV-1 cell reservoirs and sanctuary sites.
Sana-Kay Whyte-Allman, Rupert Kaul, Reina Bendayan   +2 more
doaj   +1 more source

Substrate Capture by ABC Transporters [PDF]

, 2013
Most ABC importers known to date employ a soluble substrate-binding protein to capture the ligand and donate the molecule to the translocator. The SBP can be a soluble periplasmic protein or tethered to the membrane via a lipid moiety or protein anchor ...
Poolman, Bert,, Slotboom, Dirk-Jan,, Slotboom, Dirk-Jan, Bert Poolman, Dirk-Jan Slotboom, Poolman, Bert   +5 more
core   +13 more sources

A Genomic and Transcriptomic Overview of MATE, ABC, and MFS Transporters in Citrus sinensis Interaction with Xanthomonas citri subsp. citri

Plants, 2020
The multi-antimicrobial extrusion (MATE), ATP-binding cassette (ABC), and major facilitator superfamily (MFS) are the main plant transporters families, playing an essential role in the membrane-trafficking network and plant-defense mechanism.
Maria H. M. Julião, Saura R. Silva, Jesus A. Ferro, Alessandro M. Varani   +3 more
doaj   +1 more source

Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato.

PLoS ONE, 2018
ATP binding cassette (ABC) transporters are proteins that actively mediate the transport of a wide range of molecules, such as organic acids, metal ions, phytohormones and secondary metabolites.
Peter Amoako Ofori, Ayaka Mizuno, Mami Suzuki, Enrico Martinoia, Stefan Reuscher, Koh Aoki, Daisuke Shibata, Shungo Otagaki, Shogo Matsumoto, Katsuhiro Shiratake   +9 more
doaj   +1 more source

ABC transporters in Dictyostelium discoideum development [PDF]

, 2013
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins.
Adam Kuspa, Gad Shaulsky (10030), Toplak Marko, Balaji Santhanam, Zhuchenko Olga, Adam Kuspa (45348), Marko Toplak, Gad Shaulsky, Shaulsky, Gad, Miranda Edward Roshan, Balaji Santhanam (155206), Zupan Blaz, Santhanam, Balaji, Kuspa Adam, Zupan, Blaz, Edward Roshan Miranda (446004), Marko Toplak (446006), Zhuchenko, Olga, Edward Roshan Miranda, Blaz Zupan (10031), Miranda, Edward Roshan, Olga Zhuchenko, Kuspa, Adam, Blaz Zupan, Olga Zhuchenko (446005), Santhanam Balaji, Shaulsky Gad, Toplak, Marko   +27 more
core   +1 more source

Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells

Biomolecules, 2022
ATP-binding cassette (ABC) transporters are a large superfamily of membrane transporters that facilitate the translocation of different substrates. While ABC transporters are clearly expressed in various tumor cells where they can play a role in drug ...
Rossana Visigalli, Bianca Maria Rotoli, Francesca Ferrari, Maria Di Lascia, Benedetta Riccardi, Paola Puccini, Valeria Dall’Asta, Amelia Barilli   +7 more
doaj   +1 more source

ABC transporter-mediated MXR mechanism in fish embryos and its potential role in the efflux of nanoparticles

Ecotoxicology and Environmental Safety, 2023
ATP-binding cassette (ABC) transporters are believed to protect aquatic organisms by pumping xenobiotics out, and recent investigation has suggested their involvement in the detoxification and efflux of nanoparticles (NPs), but their roles in fish ...
Jian Yin, Jia Hu, Xudong Deng, Yu Zheng, Jingjing Tian   +4 more
doaj   +1 more source

Whole-genome survey of the putative ATP-binding cassette transporter family genes in Vitis vinifera. [PDF]

PLoS ONE, 2013
The ATP-binding cassette (ABC) protein superfamily constitutes one of the largest protein families known in plants. In this report, we performed a complete inventory of ABC protein genes in Vitis vinifera, the whole genome of which has been sequenced. By
Birsen Çakır, Ozan Kılıçkaya
doaj   +1 more source

The ABCs of sterol transport

Journal of Lipid Research, 2009
Mammalian cells have developed various responses to minimize accumulation of unesterified cholesterol, as the latter can result in cell toxicity and death [reviewed in this edition by Björkhem (Björkhem, I. 2009. Are side-chain oxidized oxysterols regulators also in vivo? J. Lipid Res. In press)].
Angel, Baldán, Dragana D, Bojanic, Peter A, Edwards   +2 more
openaire   +2 more sources

Peroxisomal ABC transporters: functions and mechanism [PDF]

, 2015
Peroxisomes are arguably the most biochemically versatile of all eukaryotic organelles. Their metabolic functions vary between different organisms, between different tissue types of the same organism, and even between different developmental stages or in
Waterham, H. R., Carrier, DJ, Waterham, Hans R., Theodoulou, F. L., Carrier, D. J., Baker, Alison, Schaedler, T, Waterham, HR, van Roermund, Carlo W., Van Roermund, C. W., Baker, A, Theodoulou, Frederica L., Schaedler, Theresia, Carrier, David J., Theodoulou, FL, van Roermund, CW, Schaedler, T. A., Baker, A.   +17 more
core   +1 more source