Results 21 to 30 of about 60,654 (250)

ABC transporter-mediated MXR mechanism in fish embryos and its potential role in the efflux of nanoparticles

open access: yesEcotoxicology and Environmental Safety, 2023
ATP-binding cassette (ABC) transporters are believed to protect aquatic organisms by pumping xenobiotics out, and recent investigation has suggested their involvement in the detoxification and efflux of nanoparticles (NPs), but their roles in fish ...
Jian Yin   +4 more
doaj   +1 more source

Whole-genome survey of the putative ATP-binding cassette transporter family genes in Vitis vinifera. [PDF]

open access: yesPLoS ONE, 2013
The ATP-binding cassette (ABC) protein superfamily constitutes one of the largest protein families known in plants. In this report, we performed a complete inventory of ABC protein genes in Vitis vinifera, the whole genome of which has been sequenced. By
Birsen Çakır, Ozan Kılıçkaya
doaj   +1 more source

Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells

open access: yesBiomolecules, 2022
ATP-binding cassette (ABC) transporters are a large superfamily of membrane transporters that facilitate the translocation of different substrates. While ABC transporters are clearly expressed in various tumor cells where they can play a role in drug ...
Rossana Visigalli   +7 more
doaj   +1 more source

The ABCs of sterol transport

open access: yesJournal of Lipid Research, 2009
Mammalian cells have developed various responses to minimize accumulation of unesterified cholesterol, as the latter can result in cell toxicity and death [reviewed in this edition by Björkhem (Björkhem, I. 2009. Are side-chain oxidized oxysterols regulators also in vivo? J. Lipid Res. In press)].
Angel, Baldán   +2 more
openaire   +2 more sources

Genome-wide analysis of ATP-binding cassette (ABC) transporters in the sweetpotato whitefly, Bemisia tabaci

open access: yesBMC Genomics, 2017
Background ABC transporter superfamily is one of the largest and ubiquitous groups of proteins. Because of their role in detoxification, insect ABC transporters have gained more attention in recent years. In this study, we annotated ABC transporters from
Lixia Tian   +8 more
doaj   +1 more source

Analysis of ABC Transporter Gene Expression in Atherosclerosis

open access: yesCardiogenetics, 2021
ABC transporters are a large family of membrane proteins that transport chemically diverse substrates across the cell membrane. Disruption of transport mechanisms mediated by ABC transporters causes the development of various diseases, including ...
Stanislav Kotlyarov, Anna Kotlyarova
doaj   +1 more source

A-subclass ATP-binding cassette proteins in brain lipid homeostasis and neurodegeneration

open access: yesFrontiers in Psychiatry, 2012
The A-subclass of ATP-binding cassette (ABC) transporters comprises twelve structurally related members of the evolutionarily highly conserved superfamily of ABC transporters.
Armin P. Piehler   +3 more
doaj   +1 more source

Genome-wide analysis of ATP-binding cassette transporter provides insight to genes related to bioactive metabolite transportation in Salvia miltiorrhiza

open access: yesBMC Genomics, 2021
Background ATP-binding cassette (ABC) transporters have been found to play important roles in metabolic transport in plant cells, influencing subcellular compartmentalisation and tissue distribution of these metabolic compounds. Salvia miltiorrhiza Bunge,
Li Yan   +3 more
doaj   +1 more source

Delineating the Role of Aedes aegypti ABC Transporter Gene Family during Mosquito Development and Arboviral Infection via Transcriptome Analyses

open access: yesPathogens, 2021
Aedes aegypti acts as a vector for several arboviral diseases that impose a major socio-economic burden. Moreover, the absence of a vaccine against these diseases and drug resistance in mosquitoes necessitates the development of new control strategies ...
Vikas Kumar   +8 more
doaj   +1 more source

The effect of silymarin on expression of selected ABC transporters in the rat

open access: yesVeterinární Medicína, 2011
Silymarin (standardized extract from the seeds of the Silybum marianum) has been used in the supportive therapy of liver diseases and its cytoprotective activity is believed to be based on antioxidant properties.
R. Vecera   +4 more
doaj   +1 more source

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