Results 41 to 50 of about 74,030 (255)

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Genome-wide identification analysis of the ATP-binding cassette transporter family and expression analysis under methyl jasmonate treatment in Panax ginseng

BMC Plant Biology
The ATP-binding cassette (ABC) transporter family is one of the largest and oldest protein families and encodes a class of transmembrane transporter proteins that transport substances in living organisms.
Mengna Liu, Jianfeng He, Gaohui He, Yu Zhang, Meiping Zhang, Yi Wang, Kangyu Wang, Mingzhu Zhao   +7 more
doaj   +1 more source

Search for genes gained by horizontal gene transfer in an entomopoxvirus, with special reference to the analysis of the transfer of an ABC transporter gene

Virus Research
Although it is generally believed that large DNA viruses capture genes by horizontal gene transfer (HGT), the detailed manner of such transfer has not been fully elucidated.
Takafumi N Sugimoto, Akiya Jouraku, Wataru Mitsuhashi   +2 more
doaj   +1 more source

Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family

BMC Evolutionary Biology, 2010
Background In eukaryotes, ABC transporters that utilize the energy of ATP hydrolysis to expel cellular substrates into the environment are responsible for most of the efflux from cells. Many members of the superfamily of ABC transporters have been linked
Yuan Dongxia, Feng Lifang, Xiong Jie, Fu Chengjie, Miao Wei   +4 more
doaj   +1 more source

Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation

eLife, 2020
ABC transporters facilitate the movement of diverse molecules across cellular membranes, but how their activity is regulated post-translationally is not well understood. Here we report the crystal structure of MlaFB from E.
Ljuvica R Kolich, Ya-Ting Chang, Nicolas Coudray, Sabrina I Giacometti, Mark R MacRae, Georgia L Isom, Evelyn M Teran, Gira Bhabha, Damian C Ekiert   +8 more
doaj   +1 more source

Polyimide‐Linked Hexaazatriphenylene‐Based Porous Organic Polymer with Multiple Redox‐Active Sites as a High‐Capacity Organic Cathode for Lithium‐Ion Batteries

Advanced Materials, EarlyView.
A high‐capacity polyimide‐linked porous organic polymer (HAT‐PTO) incorporating numerous redox‐active centers is synthesized via a hydrothermal reaction, delivering a high theoretical capacity of 484 mAh g−1. In situ hybridization with carboxyl‐functionalized multiwalled carbon nanotubes enhances conductivity and stability, achieving 397 mAh g−1 at C ...
Arindam Mal, Jonathan Caroni, Asia Patriarchi, Olivera Luzanin, Rafael Ramos, Jan Bitenc, Manuel Melle‐Franco, Manuel Souto   +7 more
wiley   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source

Ferromagnetism of Molecular Beam Epitaxy‐grown Ultra‐thin Cr2Ge2Te6 Films Down to the Monolayer Limit on Si Substrates

Advanced Materials, EarlyView.
Uniform monolayer Cr2Ge2Te6 films are achieved on Si substrates by molecular beam epitaxy. Intrinsic ferromagnetism with perpendicular magnetic anisotropy is established in the films by anomalous Hall effect and superconducting quantum interference device measurements, albeit with strong magnetic fluctuations characteristic of its 2D nature.
Pengfei Ji, Ruixuan Liu, Tianchen Zhu, Yang Chen, Yitian Tong, Jinxuan Liang, Yunhe Bai, Yunyi Zang, Zuhan Geng, Fangting Chen, Xiyu Hong, Jiatong Zhang, Luyi Yang, Qi‐Kun Xue, Ke He, Xiao Feng   +15 more
wiley   +1 more source

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio). [PDF]

PLoS ONE, 2016
The ATP-binding cassette (ABC) gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC ...
Xiang Liu, Shangqi Li, Wenzhu Peng, Shuaisheng Feng, Jianxin Feng, Shahid Mahboob, Khalid A Al-Ghanim, Peng Xu   +7 more
doaj   +1 more source

Stimuli‐Responsive Hierarchical Structuring Controls Survival and Programs Hydrogelation of Supramolecular Metallofibers

Advanced Materials, EarlyView.
Aqueous Zn(II) Salphen metallofibers decorated with PNIPAM undergo reversible, multi‐stimuli‐responsive hierarchical bundling. This higher‐order structuring kinetically stabilizes the otherwise fragile assemblies against dilution, acidic hydrolysis, and transmetallation, enables selective sorting of responsive fibers, and programs hydrogelation at ...
Merlin R. Stühler, László Mérai, Kai Ludwig, Rainer Haag, Quinn A. Besford, Alex J. Plajer   +5 more
wiley   +1 more source