Results 51 to 60 of about 74,030 (255)

Photoactivable Surfactant Design for In Situ Stabilization of Hydrogel Bioelectronics

Advanced Materials, EarlyView.
Photoactivable surfactant additive enables in situ stabilization of hydrogel bioelectronics. ABSTRACT Conductive polymer hydrogels offer unique advantages for soft, stretchable biointerfaces by combining tissue‐like mechanics with high ionic conductivity.
Seungyeon Lee, Donggyun Lee, Soo‐Hwan Lee, Yuri Lee, Jooyeun Chong, Gunho Chang, Hyunjun Kim, Aejin Kim, Kyung Su Kim, Jahyun Koo, Hyojin Lee, Jiheong Kang   +11 more
wiley   +1 more source

Function and Role of ATP-Binding Cassette Transporters as Receptors for 3D-Cry Toxins

Toxins, 2019
When ABC transporter family C2 (ABCC2) and ABC transporter family B1 (ABCB1) were heterologously expressed in non-susceptible cultured cells, the cells swelled in response to Cry1A and Cry3 toxins, respectively.
Ryoichi Sato, Satomi Adegawa, Xiaoyi Li, Shiho Tanaka, Haruka Endo   +4 more
doaj   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells. [PDF]

PLoS ONE, 2011
Cancer cells eventually acquire drug resistance largely via the aberrant expression of ATP-binding cassette (ABC) transporters, ATP-dependent efflux pumps.
Ayako Nakano, Daisuke Tsuji, Hirokazu Miki, Qu Cui, Salah Mohamed El Sayed, Akishige Ikegame, Asuka Oda, Hiroe Amou, Shingen Nakamura, Takeshi Harada, Shiro Fujii, Kumiko Kagawa, Kyoko Takeuchi, Akira Sakai, Shuji Ozaki, Kazuma Okano, Takahiro Nakamura, Kohji Itoh, Toshio Matsumoto, Masahiro Abe   +19 more
doaj   +1 more source

Gout, genetics and ABC transporters [PDF]

F1000 Biology Reports, 2011
Gout is a chronic arthritic disease associated with high levels of urate in blood. Recent advances in research have permitted the identification of several new and common genetic factors underlying the disease. Among them, a polymorphism in the ABC transporter gene ATP-binding cassette transporter isoform G2 has been highlighted.
Basseville, Agnès, Bates, Susan E.
openaire   +2 more sources

Side‐Chain‐Induced Interlayer Slipping in Metalloporphyrin COFs Enables Microenvironment and Spin‐State Regulation for Photocatalytic CO2 Reduction

Advanced Materials, EarlyView.
Alkoxy chain length drives a continuous transition from eclipsed AA to a serrated, slipped AA* configuration over Co‐porphyrin COFs. A moderate slip both contracts the pore channel to enrich CO2 and suppress hydrogen evolution, and enhances collective high‐spin of Co sites, which delivers a record CO production rate with high selectivity.
Jie He, Qingxuan Chen, Minxian Zhang, Wenhao Zhao, Aoni Xu, Jinqiang Zhang, Hongqi Sun, Shaobin Wang, Xiaoguang Duan   +8 more
wiley   +1 more source

ABC transporters: the power to change [PDF]

Nature Reviews Molecular Cell Biology, 2009
ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered translocation of many substrates across membranes. The highly conserved ABC domains of ABC transporters provide the nucleotide-dependent engine that drives transport.
Rees, Douglas C., Johnson, Eric, Lewinson, Oded   +2 more
openaire   +3 more sources

Phase Diagrams Enable Solid‐State Battery Design

Advanced Materials Interfaces, EarlyView.
Batteries are non‐equilibrium devices with inherent thermodynamic driving forces to react at interfaces, regardless of kinetics or operating conditions. Chemical potential mismatches across interfaces are dissipated via interfacial reactions. In this work, it is illustrated how phase diagrams and chemical potential maps predict degradation pathways but
Nathaniel L. Skeele, Matthias T. Agne
wiley   +1 more source

Polymorphism in ABC transporter genes of Dirofilaria immitis

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Dirofilaria immitis, a filarial nematode, causes dirofilariasis in dogs, cats and occasionally in humans. Prevention of the disease has been mainly by monthly use of the macrocyclic lactone (ML) endectocides during the mosquito transmission season ...
Thangadurai Mani, Catherine Bourguinat, Roger K. Prichard   +2 more
doaj   +1 more source

Molybdenum Disulfide Bilayers Hybridized With Reduced Graphene Oxide Nanosheets for Enhanced Hydrogen Evolution Reaction

Advanced Materials Interfaces, EarlyView.
The integration of reduced graphene oxide nanosheet‐hybridized molybdenum disulfide bilayers to enhance hydrogen evolution reaction capabilities unveils thrilling opportunities for strain engineering, defect manipulation, and sophisticated twist‐angle assemblies with 2D heterostructures.
Bruno Ferreira Brischi, Gabriela Frajtag, João Pedro da Silva Mariano, Laís Fernanda Medeiros Ruela, Gustavo Duarte Verçosa, Camila Desiderio Fernandes, Murilo Santhiago, Letícia Mariê Minatogau Ferro, Leandro Merces   +8 more
wiley   +1 more source