Results 11 to 20 of about 74,030 (255)

Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background

Frontiers in Pharmacology, 2019
Mutations in ATP Binding Cassette (ABC)-transporter genes can have major effects on the bioavailability and toxicity of the drugs that are ABC-transporter substrates.
Artem Sokolov, Stephanie Ashenden, Stephanie Ashenden, Nil Sahin, Nil Sahin, Richard Lewis, Nurdan Erdem, Elif Ozaltan, Andreas Bender, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Murat Cokol, Murat Cokol, Murat Cokol, Murat Cokol   +15 more
doaj   +1 more source

Adaptation of Cupriavidus metallidurans CH34 to Toxic Zinc Concentrations Involves an Uncharacterized ABC-Type Transporter

Microorganisms, 2021
Cupriavidus metallidurans CH34 is a well-studied metal-resistant β-proteobacterium and contains a battery of genes participating in metal metabolism and resistance.
Rob Van Houdt, Joachim Vandecraen, Natalie Leys, Pieter Monsieurs, Abram Aertsen   +4 more
doaj   +1 more source

ABC-B transporter genes in Dirofilaria immitis

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the mosquito transmission season.
Catherine Bourguinat, Hua Che, Thangadurai Mani, Kathy Keller, Roger K. Prichard   +4 more
doaj   +1 more source

ATP-Binding Cassette (ABC) Transporters in Fusarium Specific Mycoparasite Sphaerodes mycoparasitica during Biotrophic Mycoparasitism

Applied Sciences, 2022
Recent transcriptomic profiling has revealed importance membrane transporters such as ATP-binding cassette (ABC) transporters in fungal necrotrophic mycoparasites.
Seon Hwa Kim, Vladimir Vujanovic
doaj   +1 more source

Plant ABC Transporters [PDF]

The Arabidopsis Book, 2011
ABC transporters constitute one of the largest protein families found in all living organisms. ABC transporters are driven by ATP hydrolysis and can act as exporters as well as importers. The plant genome encodes for more than 100 ABC transporters, largely exceeding that of other organisms.
Joohyun Kang, Jiyoung Park, Hyunju Choi, Bo Burla, Tobias Kretzschmar, Youngsook Lee, Enrico Martinoia   +6 more
openaire   +3 more sources

The ABCs of sterol transport

Journal of Lipid Research, 2009
Mammalian cells have developed various responses to minimize accumulation of unesterified cholesterol, as the latter can result in cell toxicity and death [reviewed in this edition by Björkhem (Björkhem, I. 2009. Are side-chain oxidized oxysterols regulators also in vivo? J. Lipid Res. In press)].
Angel, Baldán, Dragana D, Bojanic, Peter A, Edwards   +2 more
openaire   +2 more sources

Export of recombinant proteins in Escherichia coli using ABC transporter with an attached lipase ABC transporter recognition domain (LARD)

Microbial Cell Factories, 2009
Background ATP binding cassette (ABC) transporter secretes the protein through inner and outer membranes simultaneously in gram negative bacteria. Thermostable lipase (TliA) of Pseudomonas fluorescens SIK W1 is secreted through the ABC transporter.
Moon Yuseok, Kim Kyeongyeon, You Jinsun, Chung Chan, Kim Hoeon, Ahn Jung   +5 more
doaj   +1 more source

Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.)

BMC Genomics, 2020
Background The recent release of the reference genome sequence assembly of flax, a self-pollinated crop with 15 chromosome pairs, into chromosome-scale pseudomolecules enables the characterization of gene families.
Nadeem Khan, Frank M. You, Raju Datla, Sridhar Ravichandran, Bosen Jia, Sylvie Cloutier   +5 more
doaj   +1 more source

Karanjin interferes with ABCB1, ABCC1, and ABCG2

Journal of Pharmacy & Pharmaceutical Sciences, 2014
PURPOSE: The prominent ATP-binding cassette (ABC) transporters ABCB1, ABCC1, and ABCG2 are involved in substance transport across physiological barriers and therefore in drug absorption, distribution, and elimination.
Martin Michaelis, Florian Rothweiler, Thomas Nerreter, Mohsen Sharifi, Taravat Ghafourian, Jindrich Cinatl   +5 more
doaj   +1 more source

Relationship between conformation shift and disease related variation sites in ATP-binding cassette transporter proteins

Biophysics and Physicobiology, 2019
Transport of small molecules across the cell membrane is a crucial biological mechanism for the maintenance of the cell activity. ABC transporter family is a huge group in the transporter membrane proteins and actively transports the substrates using the
Mika Sakamoto, Hirofumi Suzuki, Kei Yura
doaj   +1 more source