Results 181 to 190 of about 60,654 (250)

The involvement of multiple ABC transporters in daunorubicin efflux in Streptomyces coeruleorubidus. [PDF]

Microb Biotechnol
Dong J, Ning J, Tian Y, Li H, Chen H, Guan W.   +5 more
europepmc   +1 more source

Spotlight on the Nucleotide: Solid‐State NMR for the Investigation of ATP Hydrolysis in the ATPase SmsC

Chemistry – A European Journal, EarlyView.
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr, Laure Decamps, Julius Schlüter, Koen Linssen, Georg Künze, Kushal Sengupta, Serena DeBeer, Thomas Wiegand   +7 more
wiley   +1 more source

A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates. [PDF]

Membranes (Basel)
Younus I, Ford RC, Prince SM.
europepmc   +1 more source

Post‐Modification of Tripyrenylenes to Enantiopure π‐Extended D3‐Symmetric Propellers

Chemistry – A European Journal, EarlyView.
The post‐modification of tripyrenylenes to π‐extended enantiopure propellers with tris‐phenanthrophenazines is presented and the chiroptical properties as well as the solid‐state packings investigated in comparison to the corresponding racemic mixtures.
Dennis Popp, Melanie Bruttel, Sebastian Möbert, Anusha Sounder Rajan, Christoph Keck, Darius Boehm, Frank Rominger, Sven M. Elbert, Michael Mastalerz   +8 more
wiley   +1 more source

Chrysosplenetin acts as a homeostasis stabilizer with dual-function in shattering Plasmodium berghei K173 resistance to artemisinin driven by both ABC transporters and heme-ROS/GSH axis. [PDF]

Parasit Vectors
Ji H, Huang Y, Tian J, Bo R, Heng X, Yang J, Huang Y, Wang X, Tan Q, Gao H, Chen L, Chen J.   +11 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Scope 3 Carbon Emissions Assessment for Manufacturing SMEs

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This paper addresses the challenges facing managers of Small‐ and Medium‐Size Enterprises (SMEs) when conducting environmental sustainability assessment at the value chain level, particularly Scope 3 Greenhouse Gases (GHG) emissions. The paper investigates issues related to data availability and data quality for Scope 3 assessment and ...
Kourosh Halat, Stephen Childe, Nick Golding, John Summerscales   +3 more
wiley   +1 more source

MiRNAs function in the development of resistance against doxorubicin in cancer cells: targeting ABC transporters. [PDF]

Front Pharmacol
Lu XY, Jin H.
europepmc   +1 more source

Time Driven Activity‐Based Costing and Social Life Cycle Assessment: An Integrated Framework for Social Sustainability Accounting

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Integrating sustainability not only into corporate strategy and product design is essential to address pressing global challenges. This study proposes a framework that integrates social life cycle assessment (S‐LCA) into time‐driven activity‐based costing (TD‐ABC) to manage both social and economic issues by assessing social impacts across ...
Widiene Essouid, Ghada Bouillass, Stéphane Trébucq, Philippe Loubet, Guido Sonnemann   +4 more
wiley   +1 more source

Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of Mycobacterium tuberculosis. [PDF]

Medicina (Kaunas)
Farhana A, Alsrhani A, Ejaz H, Alruwaili M, Alameen AAM, Manni E, Rasheed Z, Khan YS.   +7 more
europepmc   +1 more source