Results 161 to 170 of about 60,654 (250)

When less is more: Counterintuitive stoichiometries and cellular abundances are essential for ABC transporters' function. [PDF]

Sci Adv
Abdullah HQ, Levanon NL, Perach M, Grupper M, Ziv T, Lewinson O.   +5 more
europepmc   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Liver development in Atlantic cod (Gadus morhua L.) larvae: Histomorphological analysis of biliary ABC transporters and hepatic vacuolization. [PDF]

Fish Physiol Biochem
Marthinsen JL, Reitan KI, Kjørsvik E, Bardal T, Li K, Nunes B, Vassbotn AM, Olsen RE.   +7 more
europepmc   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Potential Natural Inhibitors of MRSA ABC Transporters and MecA Identified Through In Silico Approaches. [PDF]

Microorganisms
Otarigho B, Duffin PM, Falade MO.
europepmc   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

BMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu, Yongsheng Zhou, Longwei Lv   +8 more
wiley   +1 more source

Computational and experimental mapping of the allosteric network of two manganese ABC transporters. [PDF]

Protein Sci
Duman O, Kuznetsova A, Levanon NL, Grupper M, Ersoy AA, Acar B, Kessel A, Ben-Tal N, Lewinson O, Haliloglu T.   +9 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma. [PDF]

BJUI Compass
Kijima T, Takada-Owada A, Shimoda H, Kokubun H, Uematsu T, Takei K, Betsunoh H, Yashi M, Ishida K, Kamai T.   +9 more
europepmc   +1 more source