Abc transporters - Open Access .click

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2015
Neuroblastoma is the most common cancer of infancy and accounts for 15% of all pediatric oncology deaths. Survival rates of high-risk neuroblastoma remain less than 50%, with amplification of the MYCN oncogene the most important aberration associated with poor outcome. Direct transcriptional targets of MYCN include a number of ATP-binding cassette (ABC)
Denise M T, Yu +4 more
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Mammalian ABC Transporters in Health and Disease [PDF]

Annual Review of Biochemistry, 2002
The ATP-binding cassette (ABC) transporters are a family of large proteins in membranes and are able to transport a variety of compounds through membranes against steep concentration gradients at the cost of ATP hydrolysis.
Elferink, R. Oude +4 more
exaly +3 more sources

ABC Family Transporters

2019
The transport of specific molecules across lipid membranes is an essential function of all living organisms. The processes are usually mediated by specific transporters. One of the largest transporter families is the ATP-binding cassette (ABC) family.
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Interaction of ABC Transporters with Drugs

2015
ATP-binding cassette (ABC) proteins are causally related to the etiology of more than 25 human diseases. Selected members of the protein family play a role in drug disposition, drug resistance, and disease progression. The capability of ABC proteins to interact with small molecules has been well documented.
Chiba, Peter +3 more
openaire +1 more source

LIPID TRANSPORT BY ABC TRANSPORTERS