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Mitochondrial ABC transporters
Research in Microbiology, 2001In contrast to bacteria, mitochondria contain only a few ATP binding cassette (ABC) transporters in their inner membrane. The known mitochondrial ABC proteins fall into two major classes that, in the yeast Saccharomyces cerevisiae, are represented by the half-transporter Atm1p and the two closely homologous proteins Mdl1p and Mdl2p. In humans two Atm1p
R, Lill, G, Kispal
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ABC Transporters and Neuroblastoma
2015Neuroblastoma is the most common cancer of infancy and accounts for 15% of all pediatric oncology deaths. Survival rates of high-risk neuroblastoma remain less than 50%, with amplification of the MYCN oncogene the most important aberration associated with poor outcome. Direct transcriptional targets of MYCN include a number of ATP-binding cassette (ABC)
Denise M T, Yu +4 more
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Essays in Biochemistry, 2011
ABC (ATP-binding cassette) transporters are primary active membrane proteins that translocate solutes (allocrites) across lipid bilayers. The prototypical ABC transporter consists of four domains: two cytoplasmic NBDs (nucleotide-binding domains) and two TMDs (transmembrane domains).
Joseph K, Zolnerciks +3 more
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ABC (ATP-binding cassette) transporters are primary active membrane proteins that translocate solutes (allocrites) across lipid bilayers. The prototypical ABC transporter consists of four domains: two cytoplasmic NBDs (nucleotide-binding domains) and two TMDs (transmembrane domains).
Joseph K, Zolnerciks +3 more
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Insights into ABC Transport in Archaea
Journal of Bioenergetics and Biomembranes, 2004In archaea, ATP-binding cassette (ABC) transporters play a crucial role in substrate uptake, export, and osmoregulation. Archael substrate-binding-protein-dependent ABC transporters are equipped with a very high affinity for their cognate substrates which provide these organisms with the ability to efficiently scavenge substrates from their environment
Albers, Sonja Verena +3 more
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2019
The transport of specific molecules across lipid membranes is an essential function of all living organisms. The processes are usually mediated by specific transporters. One of the largest transporter families is the ATP-binding cassette (ABC) family.
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The transport of specific molecules across lipid membranes is an essential function of all living organisms. The processes are usually mediated by specific transporters. One of the largest transporter families is the ATP-binding cassette (ABC) family.
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ABC Transporters in the CNS – An Inventory
Current Pharmaceutical Biotechnology, 2011In the present review we provide a summary of ATP-binding cassette (ABC) transporters in the central nervous system (CNS). Our review is focused on transporters of the ABC A, B, C, D, and G families that have been detected in the cells of the neurovascular unit/blood-brain barrier including brain capillary endothelial cells, pericytes, astrocytes, and ...
A M S, Hartz, B, Bauer
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An update on ABC transporters of filamentous fungi – from physiological substrates to xenobiotics
Microbiological Research, 2021Jan Viglas, Petra Olejnikova
exaly
ABC transporters: lipid transport and inflammation
Current Opinion in Lipidology, 2010Timothy J, Sontag +2 more
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