Results 131 to 140 of about 37,576 (262)

Regulation and intracellular trafficking of the ABCA1 transporter

Journal of Lipid Research, 2001
The discovery of the role of the ATP-binding cassette transporter A1 (ABCA1) in mediating apolipoprotein A-I-mediated efflux has led to a dramatic increase in our knowledge of the molecular mechanisms involved in cholesterol efflux and cellular ...
Silvia Santamarina-Fojo, Alan T. Remaley, Edward B. Neufeld, H. Bryan Brewer, Jr.   +3 more
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Biology of High-Density Lipoproteins: An Update49High density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-kB/STAT1-IRF1 signaling50Homocysteine accelerated the formation of THP-1 macrophages-derived foam cells and cholesterol disorder via regulating the expressions of LXRa, ABCA1 and ABCG151Protein components of HDL as markers of cardiovascular damage in patients with arterial hypertension [PDF]

, 2016
EPC Van Der Vorst, Jian‐Ping Jin, M Mostovyak, Kosta Theodorou, MA Hoeksema, Yongzheng Wu, Pieter Goossens, Miranda Van Eck, K-a Rye, MPJ De Winther, Erik A.L. Biessen, MMP Donners, JSB Jia, Kuchmenko Ob, LS Mkhytaryan, I. N. Ievstratova, NM Vasylynchuk, TF Drobotko   +17 more
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ABCA1‐Labeled Exosomes in Serum Contain Higher MicroRNA‐193b Levels in Alzheimer’s Disease [PDF]

, 2021
Chengeng Liu, Yue Zhao, Yao Lu, Peichang Wang   +3 more
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Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]

, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A, Dickson, G, Graham, IR, Harris, JD, Owen, JS   +4 more
core  

HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux

Journal of Lipid Research, 2012
HIV infection, through the actions of viral accessory protein Nef, impairs activity of cholesterol transporter ABCA1, inhibiting cholesterol efflux from macrophages and elevating the risk of atherosclerosis. Nef also induces lipid raft formation. In this
Huanhuan L. Cui, Angela Grant, Nigora Mukhamedova, Tatiana Pushkarsky, Lucas Jennelle, Larisa Dubrovsky, Katharina Gaus, Michael L. Fitzgerald, Dmitri Sviridov, Michael Bukrinsky   +9 more
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Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1 [PDF]

, 2017
John Melchior, Scott E Street, Allison B. Andraski, Jeremy D. Furtado, Frank M. Sacks, Rebecca L. Shute, Emily I. Greve, Debi K. Swertfeger, Hailong Li, Amy S. Shah, Long Lu, W. Sean Davidson   +11 more
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ABCA1 in adipocytes regulates adipose tissue lipid content, glucose tolerance, and insulin sensitivity[S]

Journal of Lipid Research, 2014
Adipose tissue contains one of the largest reservoirs of cholesterol in the body. Adipocyte dysfunction in obesity is associated with intracellular cholesterol accumulation, and alterations in cholesterol homeostasis have been shown to alter glucose ...
Willeke de Haan, Alpana Bhattacharjee, Piers Ruddle, Martin H. Kang, Michael R. Hayden   +4 more
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Association of ABCA1 gene with Coronary Artery Disease (CAD): an overview [PDF]

, 2023
T P Yadav, Arti Yadav, Asif Jafri, Suchit Swaroop   +3 more
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Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner [PDF]

, 2017
Ting Jiang, Kun Ren, Qian Chen, Heng Li, Rong Yao, Hu Hu, Yun-Cheng Lv, Guo-Jun Zhao   +7 more
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Effects of ABCA1 R219K Polymorphism and Serum Lipid Profiles on Mild Cognitive Impairment in Type 2 Diabetes Mellitus [PDF]

, 2017
Rongrong Cai, Jing Han, Jie Sun, Rong Huang, Sai Tian, Yanjue Shen, Shaohua Wang   +6 more
openalex   +1 more source