The Effect of Eight Weeks of Aquatic Aerobic Training on ABCA1 and ABCG1 Genes Expression in the Blood Mononuclear Cells in Women After Coronary Artery Bypass Grafting [PDF]
Journal of Kerman University of Medical Sciences, 2020 Background: The aim of this research was to investigate the effect of aquatic aerobic training on regulatory factors related to Reverse Cholesterol Transport in women after coronary artery bypass grafting (CABG).
Mahdiyeh Haj Hosseini +3 more
doaj +1 more source
تأثیر هشت هفته تمرین هوازی بر برخی عوامل درگیر در متابولیسم کلسترول در هیپوکمپ و نقش آن در بهبود عملکرد شناختی رتهای نر ویستار [PDF]
فیزیولوژی ورزشی, 2020 در مطالعات بهطور گسترده به متابولیسم لیپیدهای گردش خون توجه شده است، اما در سالهای اخیر به متابولیسم لیپید در مغز بهدلیل ارتباط با برخی اختلالهای عصبی توجه بیشتری شده است.
زهرا سرلک +3 more
doaj +1 more source
ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma
Cells, 2020 The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug.
Dimas Carolina Belisario +11 more
doaj +1 more source
ABCA1 polymorphisms and Alzheimer's disease [PDF]
Neuroscience Letters, 2007 In our search for genetic factors related to the development of Alzheimer's disease, we have genotyped 332 pedigrees for three coding polymorphisms in the ABCA1 gene, two of which are known to alter plasma cholesterol levels, as well as a non-coding polymorphism within the promoter.
Wavrant-De Vrièze, Fabienne +7 more
openaire +3 more sources
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
ABCA1 and nascent HDL biogenesis [PDF]
BioFactors, 2014 AbstractABCA1 mediates the secretion of cellular free cholesterol and phospholipids to an extracellular acceptor, apolipoprotein AI, to form nascent high‐density lipoprotein (HDL). Thus, ABCA1 is a key molecule in cholesterol homeostasis. Functional studies of certain Tangier disease mutations demonstrate that ABCA1 has multiple activities, including ...
Shuhui, Wang, Jonathan D, Smith
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Role of ABCA1 in Cardiovascular Disease
Journal of Personalized Medicine, 2022 Cholesterol homeostasis plays a significant role in cardiovascular disease. Previous studies have indicated that ATP-binding cassette transporter A1 (ABCA1) is one of the most important proteins that maintains cholesterol homeostasis. ABCA1 mediates nascent high-density lipoprotein biogenesis. Upon binding with apolipoprotein A-I, ABCA1 facilitates the
Jing Wang +5 more
openaire +2 more sources
ABCA1 gene promoter methylation and sudden cardiac death
Бюллетень сибирской медицины, 2021 Aim. A study of the association of the methylation of the promoter of the ABCA1 gene with sudden cardiac death(SCD).Materials and methods. The study design is based on the case-control principle.
A. A. Ivanova +8 more
doaj +1 more source
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
, 2020 Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
Polymorphic variants of ABCA1, PMM2, and ARHGEF12 genes and the risk of glaucoma in an Iranian population [PDF]
International Journal of OphthalmologyAIM: To examine whether rs2472493 and rs248032 in the ABCA1 gene, rs3785176 in the PMM2 gene, and rs11827818 in the ARHGEF12 gene contribute to primary open angle glaucoma (POAG) in an Iranian population. METHODS: Totally 82 POAG patients and 172 healthy
Asghar Shayannia +4 more
doaj +1 more source