Results 81 to 90 of about 4,110 (154)

Methotrexate (MTX) plasma concentrations by single nucleotide polymorphism (SNP) genotypes of ATP-binding cassette subfamily C member 2 (ABCC2), ABCC4 and ABCG2.

, 2014
MTX plasma concentrations were measured at 48ABCC4 rs9516519 (A), ABCC4 rs868853 (B), ABCC4 rs2274407 (C), ABCC2 rs3740065 (D), ABCG2 rs2231137 (E).
Qi Sheng (364167), Huaiping Tian (505524), You Yin (505521), Yan Liu (25061), Fang Wang (105926), Zhiyan Lin (505523), Xiaotong Lu (505522), Ajing Xu (505525), Jian Zhang (1682)   +8 more
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DDT and lindane are potential efflux substrates of zebrafish Abcc4 in LLC-PK1 cells.

, 2014
(A and B) Effect of Abcc4 on the accumulation of MCB. Stable cell lines were exposed to 25 µM MCB and 0.1–5 µg/mL of DDT or 1–100 µg/mL of lindane for 24 hours. (C and D) Effect of Abcc4 on the excretion of DDT or lindane.
Xing Lu (1438414), Yong Long (138508), Rongze Sun (670595), Li Lin (111038), Zongbin Cui (138513), Shan Zhong (380109)   +5 more
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Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses

Cancer Medicine, 2019
Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane transport ...
Karolina Seborova, Radka Vaclavikova, Pavel Soucek, Katerina Elsnerova, Alena Bartakova, Petr Cernaj, Jiri Bouda, Lukas Rob, Martin Hruda, Pavel Dvorak   +9 more
doaj   +1 more source

Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate

Reproductive Biology and Endocrinology, 2008
Background High dietary intake of selenium or soybean isoflavones reduces prostate cancer risk. These components each affect androgen-regulated gene expression.
Setchell Kenneth DR, Lephart Edwin D, Lovinger Cameron T, Tolman Jessica R, Legg Russell L, Christensen Merrill J   +5 more
doaj   +1 more source

Correlation of Clinicopathological Characteristics with ABCC4 Expression in 121 LARC Patients Treated with Preoperative nRT.

, 2014
Abbreviations: ABCC4, ATP-binding cassette subfamily C member 4; CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; LARC, locally advanced rectal carcinoma; nRT, neoadjuvant radiotherapy.
Chang Zhang (443676), Rui Chai (509486), Yan Du (229593), Wei Zhang (405), Enda Yu (509489), Xiaoqing Zhang (80417), Guangwen Cao (388963), Junjie Xing (509488), Zhiqi Yu (509485), Xianhua Gao (509487), Chuangang Fu (509490)   +10 more
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Down-regulation of ABCC4 Expression Significantly Enhanced Irradiation-induced Suppression of Tumor Growth in Xenograft Model.

, 2014
A: Three representative mice following a total dose of 10Gy irradiation. B: Tumor volume curve (cm3) in xenograft models of RKO cells with or without ABCC4 knockdown following irradiation (P.05) in a time-dependent manner. C: The mean tumor weight (g) in
Chang Zhang (443676), Rui Chai (509486), Yan Du (229593), Wei Zhang (405), Enda Yu (509489), Xiaoqing Zhang (80417), Guangwen Cao (388963), Junjie Xing (509488), Zhiqi Yu (509485), Xianhua Gao (509487), Chuangang Fu (509490)   +10 more
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Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits

Nature Communications
A complete goat (Capra hircus) reference genome enhances analyses of genetic variation, thus providing insights into domestication and selection in goats and related species. Here, we assemble a telomere-to-telomere (T2T) gap-free genome (2.86 Gb) from a
Hui Wu, Ling-Yun Luo, Ya-Hui Zhang, Chong-Yan Zhang, Jia-Hui Huang, Dong-Xin Mo, Li-Ming Zhao, Zhi-Xin Wang, Yi-Chuan Wang, EEr He-Hua, Wen-Lin Bai, Di Han, Xing-Tang Dou, Yan-Ling Ren, Renqing Dingkao, Hai-Liang Chen, Yong Ye, Hai-Dong Du, Zhan-Qiang Zhao, Xi-Jun Wang, Shan-Gang Jia, Zhi-Hong Liu, Meng-Hua Li   +22 more
doaj   +1 more source

DS_DISC867070 – Supplemental material for Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4

, 2019
Supplemental material, DS_DISC867070 for Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4 by David Hardy, Roslyn Bill, Anass Jawhari and Alice Rothnie in SLAS ...
Alice J. Rothnie (7139039), Anass Jawhari (6458423), David Hardy (848279), Roslyn M. Bill (308029)   +3 more
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Supplementary Figure 1 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib

, 2013
PDF file - 131K, Concentration-dependence of dasatinib transport by ABCC4.
Shuiying Hu (10268480), Ken-ichi Fujita (83343), John D. Schuetz (11127821), Alice A. Gibson (10268477), Alex Sparreboom (236030), Lie Li (372905), Laura J. Janke (7498184), Brian D. Furmanski (14989523), Sharyn D. Baker (14918718), Richard T. Williams (14917794)   +9 more
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Representative Immunostains to Each Score of ABCC4 and p53 Protein in Pretreatment Biopsy Specimens.

, 2014
Left: The expression of ABCC4 protein was mainly cytomembrane and cytoplasm in epithelial rectal cancer cells (×100 magnification); Right: The expression of p53 was mainly nuclei in the rectal cancer cells (×100 magnification).
Chang Zhang (443676), Rui Chai (509486), Yan Du (229593), Wei Zhang (405), Enda Yu (509489), Xiaoqing Zhang (80417), Guangwen Cao (388963), Junjie Xing (509488), Zhiqi Yu (509485), Xianhua Gao (509487), Chuangang Fu (509490)   +10 more
core   +1 more source