Results 71 to 80 of about 14,877 (300)
ABSTRACT Background Gastrointestinal cancers (GICs) continue to dominate in terms of both incidence and mortality worldwide. Due to the absence of efficient and accurate prognostic biomarkers, the prognosis and treatment outcomes of many GICs are poor. Identifying biomarkers to predict individual clinical outcomes efficiently is a fundamental challenge
Moein Piroozkhah+3 more
wiley +1 more source
Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R.+6 more
core +4 more sources
Anoikis in cell fate, physiopathology, and therapeutic interventions
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei+12 more
wiley +1 more source
Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases
Bile acids play critical roles in platelet activation via Syk, PLCγ2, PI3K, Akt, and ERK1/2 pathway, which is also associated with Syntaxin‐11 and NCK1. Additional Bile acids (LCA) supplementation attenuated atherosclerotic plaque development and reduce the inflammation in mice.
Xianghui Zhou+9 more
wiley +1 more source
Comparative efficacy of eptifibatide and abciximab in primary angioplasty study
Rohan Jayasinghe1 Matias Yudi1 Sanjay Jayasinghe21Cardiology Department, Gold Coast Hospital, Griffith University, Queensland, Australia; 2Centre for Immunisation Research, Sydney, AustraliaBackground: Primary percutaneous intervention is the safest and ...
Rohan Jayasinghe+2 more
doaj
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua+3 more
doaj +1 more source
Cardiovascular involvement in Kawaski Disease [PDF]
This article contains a case report of a 19 month old child with Kawasaki Disease who developed bilateral giant coronary artery aneurysms.peer ...
Chintala, Kavitha+2 more
core
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu+7 more
wiley +1 more source
Background Although percutaneous coronary intervention (PCI) is becoming the standard therapy in ST-segment elevation myocardial infarction (STEMI), to date most patients, even in developed countries, are reperfused with intravenous thrombolysis or do ...
Visser Cees A+5 more
doaj +1 more source
PSAgraphics: An R Package to Support Propensity Score Analysis [PDF]
Propensity score analysis is a technique for adjusting for selection bias in observational data. Estimated propensity scores (probability of treatment given observed covariates) are used for stratification of observations. Within strata covariates should
James E. Helmreich, Robert M. Pruzek
core +1 more source