Results 71 to 80 of about 14,877 (300)

Comprehensive Multi‐Omics Analysis Reveals NPC2 and ITGAV Genes as Potential Prognostic Biomarkers in Gastrointestinal Cancers

open access: yesCancer Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background Gastrointestinal cancers (GICs) continue to dominate in terms of both incidence and mortality worldwide. Due to the absence of efficient and accurate prognostic biomarkers, the prognosis and treatment outcomes of many GICs are poor. Identifying biomarkers to predict individual clinical outcomes efficiently is a fundamental challenge
Moein Piroozkhah   +3 more
wiley   +1 more source

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

open access: yes, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R.   +6 more
core   +4 more sources

Anoikis in cell fate, physiopathology, and therapeutic interventions

open access: yesMedComm, Volume 5, Issue 10, October 2024.
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei   +12 more
wiley   +1 more source

Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases

open access: yesAdvanced Science, Volume 11, Issue 32, August 27, 2024.
Bile acids play critical roles in platelet activation via Syk, PLCγ2, PI3K, Akt, and ERK1/2 pathway, which is also associated with Syntaxin‐11 and NCK1. Additional Bile acids (LCA) supplementation attenuated atherosclerotic plaque development and reduce the inflammation in mice.
Xianghui Zhou   +9 more
wiley   +1 more source

Comparative efficacy of eptifibatide and abciximab in primary angioplasty study

open access: yesResearch Reports in Clinical Cardiology, 2011
Rohan Jayasinghe1 Matias Yudi1 Sanjay Jayasinghe21Cardiology Department, Gold Coast Hospital, Griffith University, Queensland, Australia; 2Centre for Immunisation Research, Sydney, AustraliaBackground: Primary percutaneous intervention is the safest and ...
Rohan Jayasinghe   +2 more
doaj  

Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

open access: yesCardiovascular Diabetology, 2008
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua   +3 more
doaj   +1 more source

Cardiovascular involvement in Kawaski Disease [PDF]

open access: yes, 2005
This article contains a case report of a 19 month old child with Kawasaki Disease who developed bilateral giant coronary artery aneurysms.peer ...
Chintala, Kavitha   +2 more
core  

Platelet glycoprotein IIb/IIIa antagonists in ischemic stroke patients without endovascular therapy: A meta‐analysis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 44, Issue 8, Page 675-691, August 2024.
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu   +7 more
wiley   +1 more source

Early and long-term outcome of elective stenting of the infarct-related artery in patients with viability in the infarct-area: Rationale and design of the Viability-guided Angioplasty after acute Myocardial Infarction-trial (The VIAMI-trial)

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2004
Background Although percutaneous coronary intervention (PCI) is becoming the standard therapy in ST-segment elevation myocardial infarction (STEMI), to date most patients, even in developed countries, are reperfused with intravenous thrombolysis or do ...
Visser Cees A   +5 more
doaj   +1 more source

PSAgraphics: An R Package to Support Propensity Score Analysis [PDF]

open access: yes
Propensity score analysis is a technique for adjusting for selection bias in observational data. Estimated propensity scores (probability of treatment given observed covariates) are used for stratification of observations. Within strata covariates should
James E. Helmreich, Robert M. Pruzek
core   +1 more source

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