Results 71 to 80 of about 11,480 (212)
Anoikis in cell fate, physiopathology, and therapeutic interventions
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei +12 more
wiley +1 more source
CAN3: BASELINE COST OF ILLNESS OF PARKINSON'S DISEASE IN A LARGE HEALTHCARE PLAN [PDF]
We present a mixed finite element formulation for the spatial discretization in dynamic analysis of non-isothermal variably saturated porous media using different order of approximating functions for solid displacements and fluid pressures/temperature ...
Cao, Toan Duc +3 more
core +1 more source
Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases
Bile acids play critical roles in platelet activation via Syk, PLCγ2, PI3K, Akt, and ERK1/2 pathway, which is also associated with Syntaxin‐11 and NCK1. Additional Bile acids (LCA) supplementation attenuated atherosclerotic plaque development and reduce the inflammation in mice.
Xianghui Zhou +9 more
wiley +1 more source
Angiographic findings in patients with refractory unstable angina according to troponin T status [PDF]
BACKGROUND: The CAPTURE (C7E3 fab AntiPlatelet Therapy in Unstable REfactory angina) trial enrolled patients with refractory unstable angina and documented a therapeutic benefit for abciximab, a platelet glycoprotein IIb/IIIa receptor ...
Brand, M.J.B.M. (Marcel) van den +3 more
core
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu +7 more
wiley +1 more source
Background: Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
MohammadHasan Namazi +5 more
doaj
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua +3 more
doaj +1 more source
PSAgraphics: An R Package to Support Propensity Score Analysis [PDF]
Propensity score analysis is a technique for adjusting for selection bias in observational data. Estimated propensity scores (probability of treatment given observed covariates) are used for stratification of observations. Within strata covariates should
James E. Helmreich, Robert M. Pruzek
core +1 more source
Cardiovascular involvement in Kawaski Disease [PDF]
This article contains a case report of a 19 month old child with Kawasaki Disease who developed bilateral giant coronary artery aneurysms.peer ...
Chintala, Kavitha +2 more
core
This review describes and critically evaluates computational and biological models of atherosclerosis, focusing on the hemodynamics of occluded coronary arteries. It examines emerging strategies that integrate computational and biological models and explores the advances in imaging, biofabrication, single‐cell omics, and machine learning for model ...
Thao Nhu Anne Marie Vuong +8 more
wiley +1 more source

