Results 71 to 80 of about 11,634 (196)

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources

Anoikis in cell fate, physiopathology, and therapeutic interventions

MedComm, Volume 5, Issue 10, October 2024.
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei, Xue‐Yao Jiang, Hui‐Xiang Tian, Ding‐Chao Rong, Jia‐Nan Song, Luozixian Wang, Yuan‐Shen Chen, Raymond C. B. Wong, Cheng‐Xian Guo, Lian‐Sheng Wang, Lei‐Yun Wang, Peng‐Yuan Wang, Ji‐Ye Yin   +12 more
wiley   +1 more source

Comparison between Intracoronary Abciximab and Intravenous Eptifibatide Administration during Primary Percutaneous Coronary Intervention of Acute ST-Segment Elevation Myocardial Infarction

Journal of Tehran University Heart Center, 2015
Background: Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
MohammadHasan Namazi, Morteza Safi, Hosein Vakili, Habibollah Saadat, Esfandiar Karimi, Ramin Khameneh-Bagheri   +5 more
doaj  

Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

Cardiovascular Diabetology, 2008
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua, Zhao Renyi, Pathak Alokkumar, Stouffer George A   +3 more
doaj   +1 more source

Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases

Advanced Science, Volume 11, Issue 32, August 27, 2024.
Bile acids play critical roles in platelet activation via Syk, PLCγ2, PI3K, Akt, and ERK1/2 pathway, which is also associated with Syntaxin‐11 and NCK1. Additional Bile acids (LCA) supplementation attenuated atherosclerotic plaque development and reduce the inflammation in mice.
Xianghui Zhou, Xin Zhou, Zhao Zhang, Ruirui Zhu, Meng Lu, Keyu Lv, Chao Fang, Zhangyin Ming, Zhipeng Cheng, Yu Hu   +9 more
wiley   +1 more source

Early and long-term outcome of elective stenting of the infarct-related artery in patients with viability in the infarct-area: Rationale and design of the Viability-guided Angioplasty after acute Myocardial Infarction-trial (The VIAMI-trial)

Current Controlled Trials in Cardiovascular Medicine, 2004
Background Although percutaneous coronary intervention (PCI) is becoming the standard therapy in ST-segment elevation myocardial infarction (STEMI), to date most patients, even in developed countries, are reperfused with intravenous thrombolysis or do ...
Visser Cees A, Bronzwaer Jean GF, Kamp Otto, Veen Gerrit, van Loon Ramon B, Visser Frans C   +5 more
doaj   +1 more source

PSAgraphics: An R Package to Support Propensity Score Analysis [PDF]

Propensity score analysis is a technique for adjusting for selection bias in observational data. Estimated propensity scores (probability of treatment given observed covariates) are used for stratification of observations. Within strata covariates should
James E. Helmreich, Robert M. Pruzek
core   +1 more source

Angiographic findings in patients with refractory unstable angina according to troponin T status [PDF]

, 1999
BACKGROUND: The CAPTURE (C7E3 fab AntiPlatelet Therapy in Unstable REfactory angina) trial enrolled patients with refractory unstable angina and documented a therapeutic benefit for abciximab, a platelet glycoprotein IIb/IIIa receptor ...
Brand, M.J.B.M. (Marcel) van den, Hamm, C.W. (Christian), Heeschen, C. (Christopher), Simoons, M.L. (Maarten)   +3 more
core  

Platelet glycoprotein IIb/IIIa antagonists in ischemic stroke patients without endovascular therapy: A meta‐analysis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 44, Issue 8, Page 675-691, August 2024.
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu, Cheng Yang, Wei Cao, Xinyu Zhang, Shucong Yang, Xuning Shen, Jun Xu, Huijie Yu   +7 more
wiley   +1 more source

P2Y12 Receptor Blockade Augments Glycoprotein IIb‐IIIa Antagonist Inhibition of Platelet Activation, Aggregation, and Procoagulant Activity [PDF]

, 2014
Background: New antiplatelet agents that provide greater, more consistent inhibition of the platelet ADP receptor P2Y12 may be used in combination with glycoprotein (GP) IIb‐IIIa antagonists, but their combined effect on platelet function and ...
Barnard, Marc R., Berny‐Lang, Michelle A., Frelinger, Andrew L., Jakubowski, Joseph A., Michelson, Alan D., Sugidachi, Atsuhiro   +5 more
core   +1 more source