Results 41 to 50 of about 193,069 (269)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Relationship between stress hyperglycemia ratio and gastrointestinal bleeding and mortality after coronary artery bypass grafting: a multicenter cohort study

Frontiers in Cardiovascular Medicine
BackgroundGastrointestinal bleeding after coronary artery bypass grafting (GIBCG) is a serious postoperative complication linked to increased mortality. The stress hyperglycemia ratio (SHR) has been recognized as a reliable predictor of adverse clinical ...
Jiale Dong, Jian Yang, Zhechuan Jin, Yi Jiang, Chengxiang Li, Chengxiang Li, Dongjin Wang, Huachong Ma, Zhili Ji, Zhili Ji   +9 more
doaj   +1 more source

An acute abdomen pain

BMJ Case Reports, 2009
A 61-year-old retired farmer started experiencing severe pain in his abdomen for the last 2 weeks along with abdominal distension, vomiting and inability to pass flatus or faeces. He was investigated on admission to our casualty and an abdominal x ray revealed classical features of intestinal obstruction (fig 1).
Rakesh, Biswas, Omar, Irfan, Manoj, Sharma, Gyanendra, Khare, Rajesh, Gupta, Suraj, Jain, Navneet, Mishra   +6 more
openaire   +3 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Acute pancreatitis risk in the diagnosis and management of inflammatory bowel disease: A critical focus

Open Medicine
We explored the causal relationship between pancreatitis and various autoimmune diseases using bidirectional Mendelian randomization (MR).
Zheng Feibo, Li Jinan, Ma Lina, Zhang Yu, Tu Zhengwei, Cui Yunfeng   +5 more
doaj   +1 more source

Laparoscopy in the acute abdomen [PDF]

Best Practice & Research Clinical Gastroenterology, 2014
Laparoscopy has become a routine procedure in the management of acute abdominal disease and can be considered both an excellent therapeutic and additional diagnostic tool in selected cases. However, a high level of expertise in laparoscopic and emergency surgery is required.
Navez, Benoit, Navez, Julie
openaire   +2 more sources

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Machine learning-based integration of DCE-MRI radiomics for STAT3 expression prediction and survival stratification in breast cancer

Frontiers in Immunology
ObjectiveTo explore the association between signal transducer and activator of transcription 3 (STAT3) expression, tumor immune microenvironment, and overall survival (OS) in breast cancer, and to develop a non-invasive radiomics model for early risk ...
Dong Pan, Dong Pan, Dong Pan, Cheng-Yan Zhang, Cheng-Yan Zhang, Cheng-Yan Zhang, Ya-Fei Wang, Ya-Fei Wang, Shuang Liu, Shuang Liu, Shuang Liu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu   +15 more
doaj   +1 more source

Rapunzel syndrome, a rare hairy tale: a case report [PDF]

Pediatric Emergency Medicine Journal
Rapunzel syndrome is a rare condition that typically occurs in young females with trichotillomania or trichophagia. The name “Rapunzel” was given due to the presence of trichobezoars extending from the stomach down to various parts of the ...
Nevine Macalintal, Shoshana Taube, Vinci Jones, Cornelia Muntean   +3 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source