Results 81 to 90 of about 752,260 (357)

Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal

, 2017
Warfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin.
Hasan Ökmen, Önder Akkuş, Fatih Dal, Serkan Sarı, Turgay Erginel, Meltem Küçük Yılmaz   +5 more
core   +1 more source

The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper

World Journal of Emergency Surgery, 2015
The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients with severe abdominal sepsis, however its precise role in ...
M. Sartelli, F. Abu-Zidan, L. Ansaloni, M. Bala, M. Beltrán, W. Biffl, F. Catena, O. Chiara, F. Coccolini, R. Coimbra, Z. Demetrashvili, D. Demetriades, J. Diaz, S. di Saverio, G. Fraga, W. Ghnnam, E. Griffiths, Sanjay Gupta, A. Hecker, A. Karamarkovic, V. Kong, R. Kafka-Ritsch, Y. Kluger, R. Latifi, A. Leppãniemi, J. G. Lee, M. McFarlane, S. Marwah, F. Moore, C. Ordoñez, Gerson Pereira, H. Plaudis, V. Shelat, J. Ulrych, S. Zachariah, Martin D. Zielinski, Maria Paula Garcia, E. Moore   +37 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Association between serum 25-hydroxyvitamin D levels and pulmonary function in elderly patients with chronic kidney disease: correlation analysis and exploratory predictive modelling

Frontiers in Endocrinology
BackgroundVitamin D has emerged as a significant indicator influencing pulmonary function, yet the complexity of how vitamin D affects the pulmonary function among patients with chronic kidney disease (CKD) remains incompletely elucidated.
Xuan Dai, Min Zhou, Qi Gao, Lianfang Yuan, Xiuwen Jiang, Jiarui Li, Li Zhang, Chan Guo, Naigang Gu   +8 more
doaj   +1 more source

Closing the open abdomen [PDF]

, 2007
The baseline treatment of Abdominal Compartment Syndrome is lparostomy. While this is a life saving procedure, the resulting open abdomen (OA) introduces its own challenges, mainly enteric fistula and complex ventral hernia.
Gleeson, J.W., De Costa, Alan
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Association of α-SMA/FAP-positive cancer-associated fibroblasts with clinicopathological features and prognosis in extrahepatic cholangiocarcinoma

Diagnostic Pathology
Objective This study aimed to evaluate the value of cancer-associated fibroblasts (CAFs) that positively express α-smooth muscle actin (α-SMA) and fibroblast activation protein (FAP) as survival indicators for patients with extrahepatic ...
Xiaojun Sui, Zhangqiang Zheng, Lei Yang, Dapeng Zhang, Xiangyu Sun, Ximo Wang   +5 more
doaj   +1 more source

Endoscopic ultrasound of the canine abdomen

, 2007
The aim of this study was to develop a standardized procedure for examination of the canine abdomen using endoscopic ultrasound and to describe the organs and structures that could be identified transgastrically.
Gaschen, Lorrie, Wolfram, Kathrin, Kircher, Patrick   +2 more
core   +1 more source

The open abdomen, indications, management and definitive closure

World Journal of Emergency Surgery, 2015
The indications for Open Abdomen (OA) are generally all those situations in which is ongoing the development an intra-abdominal hypertension condition (IAH), in order to prevent the development of abdominal compartmental syndrome (ACS). In fact all those
F. Coccolini, W. Biffl, F. Catena, M. Ceresoli, O. Chiara, S. Cimbanassi, L. Fattori, A. Leppãniemi, R. Manfredi, G. Montori, G. Pesenti, M. Sugrue, L. Ansaloni   +12 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source