Results 71 to 80 of about 3,651,303 (328)

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study) [PDF]

open access: yes, 2013
Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high.
Pereira Junior, Gerson Alves   +318 more
core   +1 more source

A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels

open access: yesAdvanced Robotics Research, EarlyView.
A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du   +5 more
wiley   +1 more source

Evaluation of Outcomes and Treatment Options Among Trauma Patients with Abdominal Vascular Injuries: Abdominal Vascular Injuries

open access: yes, 2023
Introduction.  Abdominal vascular injuries are rare and are associated with significant morbidity and mortality. Treatment options include nonoperative management, open repair, and endovascular procedures.
Lightwine, Kelly   +6 more
core   +1 more source

Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients

open access: yesAdvanced Robotics Research, EarlyView.
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni   +4 more
wiley   +1 more source

The current management of penetrating cardiac trauma [PDF]

open access: yes, 2012
Includes bibliographical references.The vast majority of patients with penetrating cardiac injuries do not reach the hospital alive as the pre-hospital mortality rate for these injuries is in the region of 86%.
Nicol, Andrew John
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

open access: yesAdvanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha   +5 more
wiley   +1 more source

A Retrospective Research on Intestinal Damage Due to Blunt Abdominal Trauma

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: The main cause of morbidity and death is blunt abdominal trauma. Blunt abdominal injuries may initially be difficult to detect if there are no evidence of exterior damage or alterations in the patient's vital signs.
Muralidharan Kannaian   +2 more
doaj   +1 more source

Penetrating abdominal injuries in adults seen at two teaching hospitals in ghana.

open access: yesGhana Medical Journal, 2011
BACKGROUND The incidence of penetrating abdominal injuries (PAI) has increased in the West African sub-region. OBJECTIVE To determine the pattern and management outcome of penetrating abdominal injuries (PAI) in the two main teaching hospitals in Ghana.
M. Ohene-Yeboah   +3 more
semanticscholar   +1 more source

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