Results 51 to 60 of about 111,278 (292)

Postoperative intra-abdominal sepsis

Journal of British Surgery, 1987
Abstract Postoperative intra-abdominal sepsis carries a high mortality. Diagnosis by clinical examination is often difficult, and imaging techniques may be helpful. Diagnostic laparotomy should be considered early, even in the absence of localizing signs. The use of aggressive surgical techniques may improve prognosis.
P N, Rogers, I H, Wright
openaire   +2 more sources

Inflammatory mediators, infection, sepsis, and multiorgan failure after severe trauma [PDF]

, 1992
The relation of (multiple) organ failure (OF) to the release of inflammatory mediators and the incidence of infection and sepsis was studied prospectively in 100 patients with multiple trauma (injury severity score=37).
Waydhas, Christian, Trupka, Arnold, Nast-Kolb, Dieter, Schweiberer, Leonhard, Jochum, Marianne, Fritz, Hans, Lenk, Susann, Duswald, Karl-Heimo   +7 more
core  

Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis. [PDF]

Elife
Sepsis causes millions of deaths per year worldwide and is a current global health priority declared by the WHO. Sepsis-related deaths are a result of dysregulated inflammatory immune responses indicating the need to develop strategies to target ...
Spari D, Schmid A, Sanchez-Taltavull D, Murugan S, Keller K, Ennaciri N, Salm L, Stroka D, Beldi G.   +8 more
europepmc   +3 more sources

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release : an observational study in three cohorts [PDF]

, 2010
Introduction: It has been proposed that individual genetic variation contributes to the course of severe infections and sepsis. Recent studies of single nucleotide polymorphisms (SNPs) within the endotoxin receptor and its signaling system showed an ...
Oh, Djin Ye, Koch, Alexander, David A Schwartz, van der Meer, Jos W. M., Latz, E., Eicke Latz, Djin-Ye Oh, Schumann, Ralf R, Schumann, R.R., Chryssanthi Skalioti, van der Meer, Jos WM, Jos WM van der Meer, Kumpf, Oliver, Skalioti, C., Eva Lorenz, van der Meer, Jos W.M., van der Meer, J.W., Schwartz, David A, Schlag, Peter M., Netea, M.G., Giamarellos-Bourboulis, Evangelos, Bart-Jan Kullberg, Kai Zacharowski, Mouktaroudi, Maria, Mouktaroudi, M., Latz, Eicke, Lorenz, Eva, Netea, Mihai G, Kumpf, O., Schlag, P.M., Kullberg, B.J., Schlag, Peter M, Peter M Schlag, Hamann, L., Lorenz, E., Kullberg, Bart Jan, Lutz Hamann, Ferwerda, B., Maria Mouktaroudi, Christina Routsi, Alexander Koch, Zacharowski, Kai, Oliver Kumpf, Schumann, Ralf R., Routsi, C., Evangelos J Giamarellos-Bourboulis, Bart Ferwerda, Mihai G Netea, Routsi, Christina, Koch, A., Schwartz, David A., Skalioti, Chryssanthi, Ralf R Schumann, Giamarellos-Bourboulis, E.J., Meer, J.W.M. van der, Kullberg, Bart-Jan, Hamann, Lutz, Netea, Mihai G., Giamarellos-Bourboulis, Evangelos J., Oh, D.Y., Schwartz, D.A., Oh, Djin-Ye, Zacharowski, K., Ferwerda, Bart, Giamarellos-Bourboulis, Evangelos J   +64 more
core   +1 more source

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical site infection (SSI) is a major complication after ileal pouch–anal anastomosis (IPAA) in pediatric ulcerative colitis (UC), significantly impairing quality of life. The lymphocyte‐to–C‐reactive protein ratio (LCR), a composite marker of systemic inflammation and immune/nutritional status, has emerged as a potential ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

Diagnostic and Prognostic Value of the Parameters of Lipid Peroxidation and Endogenous Intoxication in Abdominal Sepsis

Общая реаниматология, 2006
The objective of the study was to assess the diagnostic and prognostic value of the parameters of lipid peroxidation and endogenous intoxication in abdominal sepsis.
O. V. Udakova, E. V. Grigoriev
doaj   +1 more source

Prediction of Postoperative Sepsis Based on Changes in Presepsin Levels of Critically Ill Patients with Acute Kidney Injury after Abdominal Surgery

Diagnostics, 2021
Presepsin (PSP) is a viable biomarker for the detection of bacterial infection, but it lacks accuracy when acute kidney injury (AKI) develops. Herein, we evaluated the diagnostic and prognostic value of PSP in predicting postoperative sepsis after ...
Chang Hwan Kim, Eun Young Kim
doaj   +1 more source

Quizartinib in Combination With FLAG‐IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG‐QUIDA): A PETHEMA Phase I‐II Trial

American Journal of Hematology, EarlyView.
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal, Javier Zambrano Márquez, Rebeca Rodríguez‐Veiga, Eduardo Rodríguez‐Arbolí, Juan Manuel Bergua‐Burgués, Susana Vives, Montserrat Arnán, Pilar Martínez Sánchez, Pilar Herrera‐Puente, Josefina Serrano‐López, Vicente Rubio, Inmaculada Marchante‐Cepillo, Marta Cervera‐Calvo, Andrés Novo García, Rosa Fernández Martín, Cristina Gil Cortés, Carlos Rodríguez‐Medina, Victor Noriega‐Concepción, Ana Alfonso‐Piérola, Carmen Loredo, María Antuña‐Casal, Blanca Boluda, Isabel Cano‐Ferri, Evelyn Acuña‐Cruz, Laura Torres‐Miñana, Joaquín Sánchez‐García, Cristina Bilbao, Maria Teresa Gómez‐Casares, David Martínez Cuadrón, Pau Montesinos   +29 more
wiley   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source