Results 71 to 80 of about 178,563 (303)

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Lower respiratory tract infection and rapid expansion of an abdominal aortic aneurysm: a case report

Journal of Medical Case Reports, 2010
Introduction The rate of abdominal aortic aneurysm expansion is related to multiple factors. There is some evidence that inflammation can accelerate aneurysm expansion. However, the association between pulmonary sepsis and rapid abdominal aortic aneurysm
Puppala Sapna, Vohra Ravinder S, Gamie Zakareya, Naylor Steven, Kent Patrick J, Scott D   +5 more
doaj   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source

Origin of Sepsis Associated with the Short-Term Mortality of Patients: A Retrospective Study Using the eICU Collaborative Research Database

International Journal of General Medicine, 2021
Qinglin Li,1 Yingmu Tong,1 Hai Wang,1 Jie Ren,1 Sinan Liu,1,2 Tong Liu,1 Kai Qu,1 Chang Liu,1,2 Jingyao Zhang1,2 1Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, People’s Republic ...
Li Q, Tong Y, Wang H, Ren J, Liu S, Liu T, Qu K, Liu C, Zhang J   +8 more
doaj  

SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS

Медицинская иммунология, 2014
We have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e ...
V. V. Grebenuyk, N. V. Yusan
doaj   +1 more source

ROLE OF MONOCYTES IN PATHOGENESIS OF GENERALIZED PERITONITIS

Паёми Сино, 2020
Objective: To study the sepsis markers informativeness to assess the role of monocytes in the pathogenesis of generalized peritonitis (GP). Methods: The study included 160 patients with GP, who were divided into 3 groups, according to the stages of ...
A.R. SARAEV, SH.K. NAZAROV, S.G. ALI-ZADE   +2 more
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Time to Terminate Vacuum-assisted Closure and Convert to Primary Abdominal Closure in Intra-abdominal Sepsis

İstanbul Medical Journal, 2019
Introduction:There is no widely accepted surgical technique in intra-abdominal sepsis and there is also limited data on available surgical techniques and their outcomes. There is no significant difference between these techniques.
Murat Çikot, Eyüp Gemici, Nuri Alper Sahbaz   +2 more
doaj   +1 more source

MANIFISTATIONS OF ABDOMINAL SEPSIS IN PATIENTS WITH DIFFUSE PERITONITIS

Кубанский научный медицинский вестник, 2017
Aim. The study of the dynamics of the syndrome of intraperitoneal hypertension and ischemic reperfusion syndrome, which cause abdominal sepsis in patients with diffuse peritonitis. Materials and methods.
A. JA. KOROVIN, S. B. BAZLOV, M. B. ANDREEVA, V. V. NARSIYA, N. A. TRIFANOV   +4 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source