The pharmacological mechanism of Abelmoschus manihot in the treatment of chronic kidney disease [PDF]
Heliyon, 2023 Abelmoschus manihot (A.manihot) is a herbaceous flowering medicinal plant and flavonoids are its main pharmacological active ingredients. A.manihot is listed in the 2020 edition of the Chinese Pharmacopoeia for the treatment of chronic kidney disease ...
Cuiting Wei +7 more
exaly +6 more sources
Integrative physiological, transcriptomic, and metabolomic analysis of Abelmoschus manihot in response to Cd toxicity [PDF]
Frontiers in Plant ScienceRapid industrialization and urbanization have caused severe soil contamination with cadmium (Cd) necessitating effective remediation strategies. Phytoremediation is a widely adopted technology for remediating Cd-contaminated soil.
Mengxi Wu
exaly +6 more sources
Identification of the main flavonoids of Abelmoschus manihot (L.) medik and their metabolites in the treatment of diabetic nephropathy [PDF]
Frontiers in Pharmacology, 2023 Introduction: Huangkui capsule (HKC) is made from the ethanol extract of Abelmoschus manihot (L.) Medik [Malvaceae; abelmoschi corolla] and received approval from the China Food and Drug Administration (Z19990040) in 1999.
Harvest F Gu, Ge Haitao, Yu Hongmei
exaly +4 more sources
Total flavone of Abelmoschus Manihot improves colitis by promoting the growth of Akkermansia in mice [PDF]
Scientific Reports, 2021 The total flavone of Abelmoschus manihot (TFA), a compound extracted from the flowers of Abelmoschus manihot (L.) Medic, has been widely used for the treatment of Crohn's disease, chronic glomerulonephritis and other diseases.
Fan Bu +10 more
doaj +5 more sources
Screening and validation of optimal real-time PCR reference genes for Abelmoschus Manihot [PDF]
Scientific ReportsAbelmoschus Manihot is an important medicinal and edible plant known for its functional secondary metabolites. However, little is known about the key genes involved in production of secondary metabolites in A. manihot.
Qixuan Wu +4 more
doaj +4 more sources
Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot [PDF]
Molecules, 2021 Abelmoschus manihot (L.) Medic (AM), called Huangshukui in Chinese, is a widely used medicinal plant. Each part of AM has medicinal value, including Abelmoschi Radix (AR), Abelmoschi Herba (AH), Abelmoschi Folium (AF), Abelmoschi Corolla (AC), and Abelmoschi Semen (AS). However, only AC is documented in the Chinese Pharmacopoeia.
Lifang Wei, Zhichen Cai, Xunhong Liu
exaly +5 more sources
Extraction of Flavonoids from the Flowers of Abelmoschus manihot (L.) Medic by Modified Supercritical CO2 Extraction and Determination of Antioxidant and Anti-Adipogenic Activity [PDF]
Molecules, 2016 Abelmoschus manihot (L.) Medic has been used for many years in Chinese traditional medicine. In this study, supercritical CO2 plus a modifier was utilized to extract flavonoids from the flowers of Abelmoschus manihot (L.) Medic.
exaly +5 more sources
Therapeutic potential of Abelmoschus manihot: mechanisms of action and clinical use in traditional Chinese medicine formulas [PDF]
Frontiers in PharmacologyAbelmoschus manihot (L.) Medicus (AM), commonly known as Huangshukui in China, is a traditional medicinal herb. Its flowers serve as the primary active component of Huangkui Capsule (HKC), which has demonstrated therapeutic potential in various ...
Zhengyu Cao, Yaru Liu, Ge Haitao
exaly +4 more sources
Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis [PDF]
Frontiers in PharmacologyBackgroundClinical observations have recently shown that Abelmoschus manihot (L.) in the form of Huangkui capsule (HKC) and in combination with irbesartan (EB) is an effective therapy for diabetic nephropathy (DN) in patients with type 2 diabetes (T2D ...
Harvest F Gu, Ge Haitao, Yu Hongmei
exaly +4 more sources
Abelmoschus manihot alleviates insulin resistance in diabetic kidney disease through attenuation of inflammation [PDF]
BMC NephrologyBackground Emerging evidence implicates insulin resestance (IR) and chronic inflammation as interdependent drivers of diabetic kidney disease (DKD) progression.
Xiansen Wei +6 more
doaj +2 more sources