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СИСТЕМНЫЙ ПОДХОД К ОПРЕДЕЛЕНИЮ НОРМЫ И ОТКЛОНЕНИЙ В ПСИХОЛОГИЧЕСКИХ ИССЛЕДОВАНИЯХ МАТЕРИНСТВА

open access: yesНаучно-педагогическое обозрение, 2018
Раскрывается содержание термина «девиантное материнство», указываются различные степени выраженности расстройства поведения матери. Выделяются четыре основных режима функционирования системы «мать – ребенок», отражающие основные варианты практической ...
Шелехов Игорь Львович
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Advanced Processing of Images Obtained from Wide-field Astronomical Optical Systems

open access: yesActa Polytechnica, 2011
The principal aim of this paper is to present a general view of the special optical systems used for acquiring astronomical image data, commonly referred to as WFC or UWFC (Ultra Wide Field Camera), and of their transfer characteristics.
M. Řeřábek, P. Páta
doaj  

Decentration following small incision lenticule extraction (SMILE) in eyes with high myopia and its influence factors

open access: yesIndian Journal of Ophthalmology
Purpose: The purpose is to measure the decentration after small incision lenticule extraction (SMILE) in eyes with high myopia and analyze its influence factors.
Hui-Ni Lin   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Datasets and metadata supporting the published article: Somatic Genetic Aberrations in Benign Breast Disease and the Risk of Subsequent Breast Cancer

open access: green, 2020
Zexian Zeng   +9 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study of Objectives [PDF]

open access: yes
Focal length, chromatic and spherical aberration, and astigmatism testing for astronomical ...
Hartmann, J.
core   +1 more source

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