Results 121 to 130 of about 100,646 (310)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Microfluctuations of accommodation and spherical aberration

open access: yes, 1997
The microfluctuations of steady-state accommodation occur at frequencies up to about 1.5 Hz, with characteristic high and low frequency components. The high frequency components (HFC) of microfluctuations have been linked to arterial pulse (M'inn et a1 ...
Davis, Brett A., Collins, Michael J.
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Higher-order Aberration in Corneal Dystrophy.

open access: yes, 2016
Higher-order Aberration in Corneal Dystrophy.
Yumi Okuyama (3044502)   +5 more
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Comparación del LASIK convencional y el LASIK asférico en el tratamiento de la ametropía Comparison of conventional LASIK and aspheric LASIK in the treatment of ametropia

open access: yesRevista Cubana de Oftalmología, 2012
Objetivo: comparar los resultados del LASIK con patrón de ablación convencional y el asférico en la corrección de ametropías y evaluar la sensibilidad al contraste en ambos procedimientos.
Yanaisa Riverón Ruiz   +3 more
doaj  

Lens Aberration Aware Placement for Timing Yield

open access: yes, 2008
Process variations due to lens aberrations are to a large extent systematic, and can be modeled for purposes of analyses and optimiza-tions in the design phase.
Andrew B. Kahng   +3 more
core  

Aberration Correction with Low-Frequency Transmission for Medical Acoustic Imaging

open access: yes, 2010
Phase aberration is one of the major causes of deterioration in the quality of medical acoustic imaging. To suppress the effect of aberration, we employ a focused transmit beam with a low center frequency for the calculation of an aberration ...
Hirofumi Taki, Toru Sato
core   +1 more source

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