Results 91 to 100 of about 55,264 (288)

Aberration-free calibration for 3D single molecule localization microscopy

open access: yes, 2017
We propose a straightforward sample-based technique to calibrate the axial detection in 3D single molecule localization microscopy (SMLM). Using microspheres coated with fluorescent molecules, the calibration curves of PSF-shaping- or intensity-based ...
Bourg, Nicolas   +3 more
core   +3 more sources

Tissue-Saving Zernike Terms Selection in Customized Treatments for Refractive Surgery

open access: yesJournal of Optometry, 2009
Purpose: To study the possibility of performing customized refractive surgery minimising the amount of ablated tissue without compromising visual quality.
Samuel Arba-Mosquera   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Possibilities and limitations of advanced transmission electron microscopy for carbon-based nanomaterials

open access: yesBeilstein Journal of Nanotechnology, 2015
A major revolution for electron microscopy in the past decade is the introduction of aberration correction, which enables one to increase both the spatial resolution and the energy resolution to the optical limit.
Xiaoxing Ke   +2 more
doaj   +1 more source

Recent Progress on Ultrathin Metalenses for Flat Optics

open access: yesiScience, 2020
Summary: As technology advances, electrical devices such as smartphones have become more and more compact, leading to a demand for the continuous miniaturization of optical components.
Seong-Won Moon   +3 more
doaj   +1 more source

Emittance minimization for aberration correction I: Aberration correction of an electron microscope without knowing the aberration coefficients

open access: yesUltramicroscopy
Precise alignment of the electron beam is critical for successful application of scanning transmission electron microscopes (STEM) to understanding materials at atomic level. Despite the success of aberration correctors, aberration correction is still a complex process.
Desheng Ma   +8 more
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Topology Optimized Multi-layered Meta-optics

open access: yes, 2017
We propose a general topology optimization framework for metasurface inverse design that can automatically discover highly complex multi-layered meta-structures with increased functionalities.
Capasso, Federico   +4 more
core   +1 more source

Aberration correction for TEM

open access: yesMaterials Today, 2004
The transmission electron microscope (TEM) is perhaps best known for forming images at the highest resolution. It has many other capabilities, of course, forming diffraction patterns or X-ray microanalysis to name but two, but the first item to be mentioned in an instrument's specification will probably be its resolution limit. In the last few decades,
openaire   +1 more source

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