Results 71 to 80 of about 55,264 (288)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Fourier Ptychographic Neural Network Combined with Zernike Aberration Recovery and Wirtinger Flow Optimization

Sensors
Fourier ptychographic microscopy, as a computational imaging method, can reconstruct high-resolution images but suffers optical aberration, which affects its imaging quality. For this reason, this paper proposes a network model for simulating the forward
Xiaoli Wang, Zechuan Lin, Yan Wang, Jie Li, Xinbo Wang, Hao Wang   +5 more
doaj   +1 more source

Adaptive Phase Aberration Correction in Multi-Element Synthetic Aperture Imaging Systems [PDF]

Bioautomation, 2006
The problem of phase aberration correction in Multi-element Synthetic Aperture Focusing (MSAF) imaging systems is considered in this paper. In the MSAF imaging, the phase distortions caused by tissue inhomogenities can be adaptively estimated and ...
Vera Behar
doaj  

Aberration correction in holographic optical tweezers [PDF]

Optics Express, 2006
Holographic or diffractive optical components are widely implemented using spatial light modulators within optical tweezers to form multiple, and/or modified traps. We show that by further modifying the hologram design to account for residual aberrations, the fidelity of the focused beams can be significantly improved, quantified by a spot sharpness ...
Wulff, Kurt D., Cole, Daniel G., Clark, Robert L., Di Leonardo, Roberto, Leach, Jonathan, Cooper, Jon, Gibson, Graham, Padgett, Miles J.   +7 more
openaire   +4 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Comparison of aberrations after standard and customized refractive surgery [PDF]

Journal of the European Optical Society-Rapid Publications, 2013
To detect possible differences in residual wavefront aberrations between standard and customized laser refractive surgery based on mathematical modeling, the residual optical aberrations after conventional and customized laser refractive surgery were ...
Fang L., He X., Wang Y.
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IOL decentration sensitivity according to spatial frequencies

BMJ Open Ophthalmology
Background/aims Investigation of the decentration sensitivity of monofocal intraocular implants with a focus on different aberration corrections depending on different spatial frequencies.Methods Using an optical bench, the decentration sensitivities of ...
Daniel Schartmüller, Katharina Kriechbaum, Stefan Pieh, Cornelia Artmayr   +3 more
doaj   +1 more source

Chromatic aberration correction employing reinforcement learning

Optics Express, 2023
In fluorescence microscopy a multitude of labels are used that bind to different structures of biological samples. These often require excitation at different wavelengths and lead to different emission wavelengths. The presence of different wavelengths can induce chromatic aberrations, both in the optical system and induced by the sample. These lead to
Katharina Schmidt, Ning Guo, Wenjie Wang, Juergen Czarske, Nektarios Koukourakis   +4 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source