Results 221 to 230 of about 514,785 (377)

AB0184 Chromosomal aberrations are associated with disease severity in a mouse model of bleomycin-induced scleroderma [PDF]

, 2017
Roberto Luisetto, Marianna Beggio, Anna Scanu, Felipe Leite de Oliveira, Erika Pigatto, Antonella Peruffo, Elisabetta Zanatta, Francesca Oliviero, Paolo Sfriso, Leonardo Punzi, Franco Cozzi   +10 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Quantum-inspired computational wavefront shaping enables turbulence-resilient distributed aperture synthesis imaging. [PDF]

Sci Adv
Sun S, Nie ZW, Xu YK, Chang C, Chen PX, Lai PX, Liu WT.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Factors that affect distance-corrected near visual acuity in partial range of focus intraocular lenses. [PDF]

Sci Rep
Biarnés M, López E, Rodríguez L, Martín C, Insa B, Goñi I, Krolo I, Guarro M.   +7 more
europepmc   +1 more source

Widespread white matter tract aberrations in youth with familial risk for bipolar disorder

, 2015
Donna Roybal, Naama Barnea‐Goraly, Ryan Kelley, Layla Bararpour, Meghan Howe, Allan L. Reiss, Kiki Chang   +6 more
openalex   +2 more sources

Benzo(a)pyrene Diol Epoxide-Induced Chromosome 9p21 Aberrations Are Associated with Increased Risk of Bladder Cancer [PDF]

, 2008
Jian Gu, Yohei Horikawa, Meng Chen, Colin P. Dinney, Xifeng Wu   +4 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Parental and cell-division origin analysis to reduce false-positives in mosaic embryos for preimplantation genetic testing. [PDF]

Hum Reprod Open
Zhang Q, Liu G, Xiang Y, Zou Y, Chen Y, Xia Y, Xiong S, Fu T, Wang J, Jiang Y, Xiong J, Zhang X, Lu S, Liu D, Huang G, Lin T.   +15 more
europepmc   +1 more source

Transverse chromatic aberration in virtual reality head-mounted displays

, 2019
Ryan Beams, Andrea S. Kim, Aldo Badano
openalex   +1 more source