ABIETANE DITERPENOIDS FROM PLECTRANTHUS GRANDIDENTATUS [PDF]
The acetone extract of the whole plant of Plectranthus grandidentatus provided the already known abietanes royleanone, 6,7-dehydroroyleanone, horminone, 6β-hydroxyroyleanone, 7α-acetoxy-6β-hydroxyroyleanone and the abietane dimers grandidone C ...
Batista, Olga +6 more
core +3 more sources
Abietane Diterpeniods from [PDF]
Seven abietane diterpenoids were isolated from the roots of Hyptis verticillata (Labiatae). One is a novel natural product, 7-acetoxy-16-benzoxy-12-hydroxyabieta-8,12-diene-11,14-dione (1), while the other six known compounds are 11, 14 dihydroxy-12 ...
Roy B. R. Porter +2 more
doaj +3 more sources
Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS-CoV-2 Inhibitors and as Cytotoxic Agents. [PDF]
Abietanes, pimaranes and cycloartanes were characterized from different plant tissues of Taxodium mucronatum. Curvularins, mycophenolic acids and ergosterol were isolated from some fungal endophytes. The isolated compounds were in silico and in vitro evaluated as antiviral and cytotoxic agents.
Mendoza N +6 more
europepmc +2 more sources
Electrochemical oxidation of abietanes
Pine trees are coniferous, from which we can extract wood, raw tall oil, wood gum, and gum. Through the distillation of gum, we can acquire turpentine and colophony. Colophony is a complex mixture of neutral terpenes and acidic diterpenes, including abietanes, which are tricyclic diterpenoids to which abietic acid (AA) and dehydroabietic acid (DHA ...
Inês Martins +2 more
openaire +4 more sources
Abietane Diterpernoids from the Roots of Euphorbia ebracteolata [PDF]
A new ent-abietane diterpernoid, named ebracteolata D (1), along with 11 known analogues, was isolated from the roots of Euphorbia ebracteolata Hayata.
Yuan-Liang Ma +5 more
doaj +3 more sources
Plectranthus-derived Abietanes as Protein Kinase C-δ Activators: In Silico Design, Human Serum Albumin Interaction, and Stability Evaluation. [PDF]
ABSTRACT Cancer remains a major global health challenge. Among protein kinases (PKCs), PKC‐δ acts as a tumor suppressor in colon cancer and represents a valuable therapeutic target. Human serum albumin (HSA) is gaining attention as an efficient drug carrier, while Plectranthus spp. offers a rich source of bioactive compounds.
Isca VMS +4 more
europepmc +2 more sources
Exploring the Role of Phytoconstituent From <i>Euphorbia neriifolia</i> Targeting IL-17A in Psoriasis: In Silico and In Vitro Study. [PDF]
This research explores the various phytoconstituents from Euphorbia neriifolia targeting IL‐17A through in silico and in vitro studies for its role in the more precise and effective therapy in Psoriasis. Molecular docking revealed Taraxerol, Glutinol acetate, and Epifriedelanol showed strong IL‐17A binding (−10.3 to −10.0 kcal/mol), outperforming ...
Sharma N +6 more
europepmc +2 more sources
Abietane Diterpenes of the Genus Plectranthus sensu lato
Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various ailments of
Mária Gáborová +2 more
doaj +1 more source
Anticoronavirus Evaluation of Antimicrobial Diterpenoids: Application of New Ferruginol Analogues
The abietane diterpene (+)-ferruginol (1), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such as antimicrobial activity, including antiviral.
Mihayl Varbanov +2 more
doaj +1 more source
As part of our studies on antiprotozoal activity of approved herbal medicinal products, we previously found that a commercial tincture from Salvia officinalis L. (common Sage, Lamiaceae) possesses high activity against Trypanosoma brucei rhodesiense (Tbr)
Núria Llurba Montesino +3 more
doaj +1 more source

