Results 1 to 10 of about 22,446 (231)

Characterization and Identification of the Ent-Kaurane Diterpenoids in Isodonis Excisoidis Herba Using UHPLC-LTQ-Orbitrap-MS [PDF]

Molecules
Isodonis Excisoidis Herba (IEH) is a newly discovered herbal medicine used to treat esophageal cancer, chronic pharyngitis, and hepatitis, and ent-kaurane diterpenoids are its main active components. However, systematic studies on the chemical profile of
Xiaoya Sun, Lingxia Zhang, Conglong Lian, Suiqing Chen, Liping Dai, Yaozu Han   +5 more
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Recent Advances in Ent-Abietane Diterpenes: Natural Sources, Biological Activities and Total Synthesis [PDF]

Molecules
Ent-abietane diterpenoids constitute a class of terpenes with a C20 carbon skeleton that underlie a wide range of biological activities. Ent-abietane diterpenoids, enantiomeric to the abietane counterparts, represent a family of diterpenoid natural ...
Lu Li, Yongjie Zhu, Haixia Deng, Liqiong Xie, Chang-Bo Zheng, Jian-Neng Yao, Ji Li   +6 more
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Rosanoid diterpenoids: structural diversity, classification and biological activities [PDF]

ADMET and DMPK
Background and purpose: Rosanoid diterpenoids, including ent-rosane and rosane diterpenoids, are structurally unique and bioactive subclass diterpenes characterized by a tricyclic carbon skeleton.
Sabrin R. M. Ibrahim, Hani Z. Asfour , Gamal A. Mohamed, Nabil A. Alhakamy , Hossam M. Abdallah, Hagar M. Mohamed   +5 more
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Heterologous biosynthesis of cotylenol and concise synthesis of fusicoccane diterpenoids [PDF]

Beilstein Journal of Organic Chemistry
A novel strategy for the synthesis of fusicoccane diterpenoids is reported. By harnessing the biosynthetic pathways of brassicicenes and fusicoccins, cotylenol was produced in an engineered Aspergillus oryzae strain.
Ye Yuan, Zhenhua Guan, Xue-Jie Zhang, Nanyu Yao, Wenling Yuan, Yonghui Zhang, Ying Ye, Zheng Xiang   +7 more
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Overview of Primary and Secondary Metabolites of Rugulopteryx okamurae Seaweed: Assessing Bioactivity, Scalability, and Molecular Mechanisms [PDF]

Marine Drugs
Rugulopteryx okamurae is an invasive brown alga that has colonised Mediterranean and northeastern Atlantic coastlines, posing significant ecological and economic challenges.
Ana Minerva García-Cervantes, José A. M. Prates, José Luis Guil-Guerrero   +2 more
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Ghardaqenoids A–F: Six New Diterpenoids from the South China Sea Soft Coral Heteroxenia ghardaqensis with Lipid-Lowering Activity via the Activation of the AMPK Signaling Pathway [PDF]

Marine Drugs
Six new diterpenoids, including two verticillane ghardaqenoids A–B (1–2) and four dolabellane ghardaqenoids C–F (3–6), were isolated from the soft coral Heteroxenia ghardaqensis collected in the South China Sea.
Yue Zhang, Xin Han, Juan Wu, Shan Liu, Hongwei Zhang, Lili Zhao, Guoqiang Li   +6 more
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Tripterygium glycosides: recent advances in mechanisms, therapeutic applications, and safety optimization [PDF]

Frontiers in Medicine
Tripterygium glycosides (TG), bioactive extracts derived from Tripterygium wilfordii Hook F., possess potent anti-inflammatory and immunomodulatory properties, making them promising therapeutic candidates for a range of autoimmune and inflammatory ...
Yujie Jin, Yujie Jin, Yujie Jin, Yongxin Cui, Yongxin Cui, Yongxin Cui, Zhanyan Zhang, Zhanyan Zhang, Chenglin Huang, Ruoting Tong, Ruoting Tong, Ye Ling, Ye Ling, Qirui Pei, Qirui Pei, Yan Ma, Yan Ma, Qixia Zhan, Xiaojian Leng, Junjun He, Junjun He, Junjun He, Lizhuo Wang, Lizhuo Wang, Jialin Gao, Jialin Gao, Jialin Gao   +26 more
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Diterpenes Specially Produced by Fungi: Structures, Biological Activities, and Biosynthesis (2010–2020)

Journal of Fungi, 2022
Fungi have traditionally been a very rewarding source of biologically active natural products, while diterpenoids from fungi, such as the cyathane-type diterpenoids from Cyathus and Hericium sp., the fusicoccane-type diterpenoids from Fusicoccum and ...
Fa-Lei Zhang, Tao Feng
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Stepwise Diagnostic Product Ions Filtering Strategy for Rapid Discovery of Diterpenoids in Scutellaria barbata Based on UHPLC-Q-Exactive-Orbitrap-MS

Molecules, 2022
Diterpenoids are considered the major bioactive components in Scutellaria barbata to treat cancer and inflammation, but few comprehensive profiling studies of diterpenoids have been reported.
Xinhua Zhou, Xu Chen, Liping Fan, Huirong Dong, Yan Ren, Xiangming Chen   +5 more
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Identification of the antibacterial action mechanism of diterpenoids through transcriptome profiling

Frontiers in Microbiology, 2022
Effective antibacterial substances of Aralia continentalis have anti-biofilm and bactericidal activity to the oral pathogen Streptococcus mutans. In this study, three compounds extracted from A.
Keumok Moon, Sungmin Hwang, Hyeon-Jeong Lee, Eunhye Jo, Jeong Nam Kim, Jeong Nam Kim, Jaeho Cha, Jaeho Cha, Jaeho Cha   +8 more
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