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A synthetic approach to abiogenesis
Nature Methods, 2014Synthetic biology seeks to probe fundamental aspects of biological form and function by construction (resynthesis) rather than deconstruction (analysis). Here we discuss how such an approach could be applied to assemble synthetic quasibiological systems able to replicate and evolve, illuminating universal properties of life and the search for its ...
James, Attwater, Philipp, Holliger
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Precambrian ELF and Abiogenesis
1974In 1938, Oparin, in his book, “The Origin of Life”, proposed environmental conditions under which life or its chemical precursors could have been synthesized on the primitive Earth. Though unchanged in essential features, Oparin’s conditions have been subsequently refined.
F. E. Cole, E. R. Graf
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Nucleic acids: function and potential for abiogenesis
Quarterly Reviews of Biophysics, 2017AbstractThe emergence of functional cooperation between the three main classes of biomolecules – nucleic acids, peptides and lipids – defines life at the molecular level. However, how such mutually interdependent molecular systems emerged from prebiotic chemistry remains a mystery. A key hypothesis, formulated by Crick, Orgel and Woese over 40 year ago,
Falk, Wachowius +2 more
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Cysteine Chemistry in Connection with Abiogenesis
European Journal of Organic Chemistry, 2020Theoretical and experimental work has been conducted about possible prebiotic syntheses of cysteine. Activated derivatives of this amino acid can oligomerize and polymerize to afford various poly‐thiazolines and cysteine‐rich chains.
Shalayel, Ibrahim +5 more
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Abiogenesis and the reverse Hofmeister effect
Nature Chemistry, 2018Bruce C. Gibb takes us on a journey through the physical and chemical evolution of planet Earth and suggests that the reverse Hofmeister effect, the phenomenon whereby poorly solvated ions associate in water, could be a powerful driving force towards the first hint of life on the rock we call home.
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Two Experiments in Abiogenesis
Inference: International Review of Science, 2016Two new papers on prebiotic chemistry are reviewed by James Tour. The first claims to find further support for the RNA World hypothesis and the second suggests that nucleotide formation and selection may have been robust processes on the prebiotic Earth. Tour expresses skepticism on both counts.
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Abiogenesis as a theoretical challenge: Some reflections
Journal of Theoretical Biology, 2016In this paper I will reflect on the intellectual rationale underlying the origin of life scientific research efforts by reconsidering some of its conceptual premises and difficulties.
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Abiogenesis and the Second Law of Thermodynamics
2020Abiogenesis, life arising from non-living matter, is reconsidered. A historic account is given from Darwin to the present with special consideration of the incipient relationship between quantum theory and life processes. Recent ideas relating to the spontaneous emergence of life are considered and evaluated, including the work on self-organizing ...
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