Results 61 to 70 of about 1,182 (152)

Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery

open access: yesActa Physiologica, Volume 241, Issue S734, July 2025.
ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley   +1 more source

Abiogenesis: discussion on the origin and evolution of life [PDF]

open access: yes, 2022
openL’abiogenesi è il presunto processo attraverso il quale la vita si è generata spontaneamente sulla Terra partendo da materiale non vivente.
PERUZZO, MARCO
core  

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self‐Organizing Biosystems via Amyloid Formation

open access: yesChemistry – A European Journal, Volume 31, Issue 29, May 22, 2025.
APR‐A, an aggregation‐prone oligopeptide, can convert into APR‐B through distinct mutational pathways—some exclusively forming insoluble amyloid‐like peptides, others yielding water‐soluble, non‐aggregating monomers. These orthogonal pathways in chemical evolution may have driven macromolecular assembly under prebiotic Earth conditions, potentially ...
Fruzsina Bencs   +7 more
wiley   +1 more source

The Conditional Abiogenesis Problem Part II

open access: yes
**The Conditional Abiogenesis Problem — Part II: Sufficient Physical Conditions for Conditional Necessity** This working paper develops a theoretical framework for identifying the physical and dynamical conditions under which the transition from abiotic
Rudolf Schaefer
core   +2 more sources

The remarkable cell: Intelligently designed or by evolutionary process?

open access: yesVerbum et Ecclesia, 2013
The objective of this article was to deal with the challenging theme of the Origin of Life. Science has been arguing the when and how of the beginning of life for centuries.
Mark Pretorius
doaj   +1 more source

Factoring Origin of Life Hypotheses into the Search for Life in the Solar System and Beyond

open access: yesLife, 2020
Two widely-cited alternative hypotheses propose geological localities and biochemical mechanisms for life’s origins. The first states that chemical energy available in submarine hydrothermal vents supported the formation of organic compounds and ...
Alex Longo, Bruce Damer
doaj   +1 more source

Evaluation of antiobesogenic properties of fermented foods: In silico insights

open access: yesJournal of Food Science, Volume 90, Issue 3, March 2025.
Abstract Obesity prevalence has steadily increased over the past decades. Standard approaches, such as increased energy expenditure, lifestyle changes, a balanced diet, and the use of specific drugs, are the conventional strategies for preventing or treating the disease and its associated complications.
Abdullahi Adekilekun Jimoh   +1 more
wiley   +1 more source

Step‐by‐Step Towards Biological Homochirality – from Prebiotic Randomness To Perfect Asymmetry

open access: yesChemistry – An Asian Journal, Volume 20, Issue 1, January 2, 2025.
This review focuses on the theories related to the emergence of biological homochirality, from assembly of building blocks at the monomer level, to polymerization into functional homochiral biopolymers. Abstract The history of life's formation and the origin of its stereochemistry are nearly as multifaceted as the life itself.
Ivana Mejdrová   +2 more
wiley   +1 more source

Abiogenesis and the Second Law of Thermodynamics

open access: yes, 2020
Abiogenesis, life arising from non-living matter, is reconsidered. A historic account is given from Darwin to the present with special consideration of the incipient relationship between quantum theory and life processes.
Erkki J. Brändas, Brändas, Erkki,
core   +1 more source

Abiogenesis not required to explain the origin of volcanic-hydrothermal hydrocarbons [PDF]

open access: yes, 2019
Abiotic formation of n-alkane hydrocarbons has been postulated to occur within Earth's crust. Apparent evidence was primarily based on uncommon carbon and hydrogen isotope distribution patterns that set methane and its higher chain homologues apart from ...
Hofmann, S.   +30 more
core   +2 more sources

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