Results 71 to 80 of about 2,618 (222)
FEBS Letters, Volume 599, Issue 19, Page 2693-2705, October 2025.The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley +1 more source
Frontiers in Synthetic BiologyFor much of recorded history, the question “Where does life come from?” was answered with certainty: Aristotle’s doctrine of spontaneous generation and staged “ensoulment” defined both natural philosophy and Christian scholasticism.
Nediljko Budisa, David B. Levin
doaj +1 more source
Subjective Evolution of Consciousness in Modern Science and Vedāntic Philosophy: Particulate Concept to Quantum Mechanics in Modern Science and Śūnyavāda to Acintya-Bhedābheda-Tattva in Vedānta [PDF]
, 2019 How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from nothing or śūnya (as proposed by Stephen Hawking, among others) proves to be dissembling, since the quantum vacuum can hardly be considered a ...
Ph D. Shanta, PhD
core
Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery
Acta Physiologica, Volume 241, Issue S734, July 2025.ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley +1 more source
THE PROTOBIOLOGICAL THEORY OF CEILINGS AND FLOORS, OR CHEMICAL EVOLUTION AS A PLANETARY PROCESS [PDF]
Filozofia i NaukaThe article presents a modern protobiological theory based on the classical archetype. It connects the issues of origins of life with the theory of the hierarchy of matter and recognizes that error correction occurs within hierarchical and dynamic living
Alicja Kubica
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Drake Equation for the Multiverse: From the String Landscape to Complex Life
, 2010 It is argued that selection criteria usually referred to as "anthropic conditions" for the existence of intelligent (typical) observers widely adopted in cosmology amount only to preconditions for primitive life.
Baross J. A. +16 more
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Life on Mars? The physiological perspective
Experimental Physiology, EarlyView.
Ronan M. G. Berg, Damian M. Bailey
wiley +1 more source
Chemistry – A European Journal, Volume 31, Issue 29, May 22, 2025.APR‐A, an aggregation‐prone oligopeptide, can convert into APR‐B through distinct mutational pathways—some exclusively forming insoluble amyloid‐like peptides, others yielding water‐soluble, non‐aggregating monomers. These orthogonal pathways in chemical evolution may have driven macromolecular assembly under prebiotic Earth conditions, potentially ...
Fruzsina Bencs +7 more
wiley +1 more source
Evaluation of antiobesogenic properties of fermented foods: In silico insights
Journal of Food Science, Volume 90, Issue 3, March 2025.Abstract Obesity prevalence has steadily increased over the past decades. Standard approaches, such as increased energy expenditure, lifestyle changes, a balanced diet, and the use of specific drugs, are the conventional strategies for preventing or treating the disease and its associated complications.
Abdullahi Adekilekun Jimoh +1 more
wiley +1 more source
Heroical Apatheism: Mala Fide Bootstrapping Obligations [PDF]
, 2018 Discussions on hypothetical gods virtually always focus on the latter’s existence or nonexistence. However, this is only the secondary question. Heroical apatheism distinguishes these questions from the primary question, which pertains to the importance ...
Von Hegner, Ian
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