bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia [PDF]
, 1986 A De Klein +9 more
openalex +1 more source
Small Science, EarlyView.Hyaluronic acid‐decorated imatinib‐loaded liposomes are developed to specific target CD44 receptor expressed by interstitial lung fibrosis cells, demonstrating higher uptake than empty liposomes. Based on promising in vitro data, they are administered intratracheally and intraperitoneally in a mouse bleomycin model, assessing their ability to decrease ...
Sara Bozzini +13 more
wiley +1 more source
Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias
Advances in Hematology, 2015 BCR-ABL-mediated leukemias, either Chronic Myeloid Leukemia (CML) or Philadelphia positive Acute Lymphoblastic Leukemia (ALL), are the paradigm of targeted molecular therapy of cancer due to the impressive clinical responses obtained with BCR-ABL ...
Alessandro Morotti +6 more
doaj +1 more source
Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis
Cell Communication and Signaling, 2019 Background Deregulated c-Abl activity has been intensively studied in a variety of solid tumors and leukemia. The class-I carcinogen Helicobacter pylori (Hp) activates the non-receptor tyrosine kinase c-Abl to phosphorylate the oncoprotein cytotoxin ...
Gernot Posselt +13 more
doaj +1 more source
Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes. [PDF]
, 1986 Kevin L. Holmes +3 more
openalex +1 more source
High‐Resolution Heterogeneous Hydrogel Printing Using a Home Projector
Small Methods, EarlyView.This study presents a high‐resolution hydrogel printing method using photoreactive polyvinyl alcohol bearing styrylpyridinium groups (PVA‐SbQ) and a standard digital projector to spatially control light exposure. This approach enables precise tuning of crosslinking, allowing the integration of soft/tough and high/low swelling regions within a single ...
Zhangkang Li +8 more
wiley +1 more source
PLoS ONEMethotrexate (MTX) is classified as an antimetabolite. It's commonly used to treat lung cancer. MTX is an immunosuppressant following the above-mentioned mechanism of action due to its poor selectivity.
Samaa Abdullah +6 more
doaj +1 more source
Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines. [PDF]
, 1988 Mark W. Renshaw +2 more
openalex +1 more source
Iatrogenic pulsus alternans in a dog undergoing median sternotomy
Veterinary Record Case Reports, EarlyView.Abstract A 6‐year‐old, 21.8 kg, female, spayed Siberian husky was referred for management of a spontaneous bilateral pneumothorax, due to a ruptured pulmonary bleb. During surgery, sterile saline was instilled on three occasions in order to locate the damaged lung tissue and ensure complete ligation.
Marie‐Line Doï +2 more
wiley +1 more source
Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus [PDF]
, 1985 Sequences termed v-abl, which encode the protein-tyrosine kinase activity of Abelson murine leukemia virus, have been expressed in Escherichia coli as a fusion product (ptabl50 kinase).
Baltimore, David +4 more
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