Results 111 to 120 of about 217,258 (295)

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Multiple Equilibria in a Single-Column Model of the Tropical Atmosphere

open access: yes, 2007
A single-column model run under the weak temperature gradient approximation, a parameterization of large-scale dynamics appropriate for the tropical atmosphere, is shown to have multiple stable equilibria.
A. H. Sobel   +21 more
core   +1 more source

Launch support: Managing complementor bottlenecks in the disruptive innovation of small satellites

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Through both qualitative and quantitative analyses of large‐rocket providers' support for small‐satellite manufacturers before the emergence of small rockets, we examine how disruptors to an incumbent ecosystem gain support from complementors of the incumbent technology.
Yue Song, Yue Maggie Zhou, Xiaoping Zhao
wiley   +1 more source

c-Abl Deficiency Provides Synaptic Resiliency Against Aβ-Oligomers

open access: yesFrontiers in Cellular Neuroscience, 2019
Spine pathology has been implicated in the early onset of Alzheimer’s disease (AD), where Aβ-Oligomers (AβOs) cause synaptic dysfunction and loss.
Daniela A. Gutierrez   +5 more
doaj   +1 more source

Revised supplemental figures from Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor–Sensitive and -Resistant Chronic Myeloid Leukemia

open access: gold, 2023
Isabel Ben‐Batalla   +21 more
openalex   +1 more source

ABL (c-abl oncogene, receptor tyrosine kinase) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2010
Review on ABL (c-abl oncogene, receptor tyrosine kinase), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

The Development of Indo‐Iranian Voiced Fricatives

open access: yesTransactions of the Philological Society, Volume 123, Issue 1, Page 97-115, March 2025.
Abstract The development of voiced sibilants is a long‐standing puzzle in Indo‐Iranian historical phonology. In Vedic, all voiced sibilants are lost from the system, but the details of this loss are complex and subject to debate. The most intriguing development concerns the word‐final ‐aḥ to ‐o in sandhi.
Gašper Beguš
wiley   +1 more source

Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

open access: yesMolecular Cancer, 2019
Background Long noncoding RNAs (lncRNAs), defined as the transcripts longer than 200 nt without protein-coding capacity, have been found to be aberrantly expressed in diverse human diseases including cancer.
Xuefei Wang   +9 more
doaj   +1 more source

Discussion: Time-Symmetric Quantum Counterfactuals [PDF]

open access: yes, 2003
There is a trend to consider counterfactuals as invariably time-asymmetric. Recently, this trend manifested itself in the controversy about validity of counterfactual application of a time-symmetric quantum probability rule.
Vaidman, Lev
core   +1 more source

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